Quiz 8 Notes from SI- Penicillin: 3 on PCN/cephalosporin o Teaching w/ PCN: allergy bracelet, take it w/ food, take w/ yogurt, take it until it’sdone, may cause GI upset o Know there is a cross-sensitivity! o PCN inactivates aminoglycocides… Can’t mix with aminoglycocides o Requires adjustment with renal ps (don’t change the dose in renal pts?)o Toxicity lowo *Know how it works on cells!!!!! - Vanco: *3 questions on vanco! o Ototoxicityo Red mans syndrome if given too fast o Give the test dose when starting vancoo Use for MRSA, C. Diffo Know ALL the ADRs - Gentomasion: o Ototoxico *Look into hepatotoxicity (and the rest of the toxicities) - Tx for C. Diff:o Vanco and sulfa- Aminoglycocides: 2 questions on these!o Don’t mix w/ PCN????? (ask her tomorrow about this) o Good for staph and strep infectionso Monitor peaks and troughs, binds to kidneys (BUN and creatinine, edema, HTN, s/s of kidney failure. *check theseo Nausea, Vomiting, Loss of appetite, Fatigue and weakness, Sleep problems, Changes in urine output, Decreased mental sharpness, Muscle twitches and cramps, Hiccups, Swelling of the feet and ankles, Persistent itching, Chest pain: if fluid accumulates around the lining of the heart, Shortness of breath: if fluid accumulates in the lungs, High blood pressure (hypertension) that's difficult to controlo Increased BUN and serum creatinine- Erythromisin: o Broad spectrum - Zithromaxo Z-pack, only take once a dayo ADRs: GI-diarrhea (not as bad as erythro) - Look over generations of cephalosporin’s o Know different ways they worko Know what each specific generation is used foro MOA of each- Tetrocycolines:o Calcium bindings (don’t give with milk, calcium, iron, pregnant)o Don’t give to kids less than 8 or pregnant peopleo More ADRs then PCN and
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