BIO 240: STUDY GUIDE 2: THE CELLULAR LEVEL OF ORGANIZATION

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Cell
Smallest structural and functional unit of an organism.
Cytology
Branch of biology that studies plants & animal cells' function and structure.
4 Principle parts of general animal cell
Plasma cell membrane, cytosol, organelles, inclusions
Fluid-mosaic Model
Composed of two main chemical components: a lipid bilayer embedded with protein molecules.
Integral proteins in the membrane
Penetrate (some go completely) through wall, act as channels, act as transport, receptor, enzyme, identity.
Peripheral proteins in the membrane
Anchors to integral proteins.
3 main functions of plasma membrane
Communication (w/cell by membrane, other cells, foreign cells, & ligands) Electrochemical Gradient (chemicals form by chemical layout of membrane. Electrical forms by diff in charges) Selective Permeability (regulates entry & exit of substances)
4 Factors affecting permeability of cell membrane
lipid permeability, size, charge, presence of specific channels/transporters
Difference between active/passive
Active requires ATP, passive does not.
Diffusion
All substances have kinetic energy. Constantly moving cells collide & mix; move down a concentration gradient. (passive)
Facilitated diffusion
Carrier transport chemical down concentration gradient without utilizing ATP. (passive)
Osmosis
Net flow of water through selective permeable membranes. Results from chemical concentration difference, or mechanical force. (passive)
Filtration
Hydrostatic pressure forces fluid through selective permeable membrane; especially capillary wall (passive)
Dialysis
Separation of particles in fluid based on differences in the ability to pass membranes. (active)
Active Transport
Transport of material through selective permeable membrane, UP its concentration gradient via ATP (active).
Exocytosis
Active transport where cell expends energy to discharge large substances from the cell; waste/gland products. (active)
Pinocytosis
Form of endocytosis, where plasma membrane sinks inward and imbibes droplets of extracellular fluid.
Phagocytosis
Form of endocytosis where pseudo-pods engulf foreign material enclosing it in a cytoplasmic vesicle called phagosome
Intracellular fluid contains how much NaCl?
.9% NaCl compared to water.
Microvilli
Smallest outgrowth from permeable membrane; increases surface area and aids in absorption and some sensory processes.
Cilia
Hairlike projection from apical surface of epithelial cells. Motile: propel matter across surface of epithelium. Nonmotile: some sensory processes.
Flagella
Slender/threadlike appendages that aid in "swimming"
3 Functions of Cytoplasm
Medium where metabolic processes occur. Suspend organelles. Receives raw material from extracellular fluid
Extracellular Materials
Complex misture of non-living materials that makes the matrix-carbs&proteins are minerals in bone matrix
Mitosis
Cell division resulting in 2 identical daughter cells.
'Crossing Over'
Process where paternal and maternal chromosomes exchange segments of DNA. Creates new combinations of genes and contributes to genetic variety in offspring.
Role of DNA in the cell.
Carries instructions called genes for the synthesis of proteins.
Role of RNA in the cell
Function of the three types is to interpret code in DNA and use those instructions to synthesize proteins.
Transcription
The process of copying genetic instructions from DNA to RNA via RNA polymerase (attaches to DNA to form RNA) DNA: C, A, T. RNA: G, U
Translation
Converts the language of nucleotides into the language of amino acids. mRNA carries info from nucleus to cytoplasm. tRNA binds a free amino acid in cytosol & delivers to ribosome (become protein chain). rRNA allows tRNA to attach and makes protein
3 Steps of translation
Initiation, elongation, termination
Inheritance
Genetic characters transmitted from parent to offspring, taken collectively.
Homologues
Homologous chromosomes. 2 members of each pair of chromosomes. One inherited from mother, one from father.
Genotype/Phenotype
Geno: chemical makeup of an allele. Pheno: physical expression of an allele.
Homozygous/Heterozygous
homo: having 2 identical alleles. hetero: chromosome has different alleles for that gene.
Incomplete Dominance
Two different alleles are present and the phenotype is intermediate between the traits.
Co-dominance
Alleles are equally dominant. Both are phenotypically expressed.
Multiple-allele Inheritance
More than 2 different alleles for a given gene in a gene pool. (ABO blood type has 3 alleles)
Polygenic Inheritance
Phenomenon which genes at more than or equal to 2 loci, or even on different chromosomes, contribute to a single phenotypic trait.
Sex-linked Inheritance
Carried on the X or Y chromosome, and therefore tend to be inherited by one sex more than the other.

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