CHM 6154 (Fall, 2013)Chemical SeparationsInstructor: Charles Cao ([email protected]), 226 Leigh HallLectures: M, W, F, 7th Period (1:55 pm to 2:45 pm), 104 Leigh HallOffice hours: W, F, - 8th Period (3:00 pm to 3:50 pm), or by appointmentWebsite: http://www.chem.ufl.edu/~cao/CHM6154/index.htmlRequirement: Strong background in calculus and thermodynamicsTextbook: Unified Separation Science by J. Calvin Giddings (John Wiley & Sons, Inc.) Reference book: The Essence of Chromatography by Colin Poole (Elsevier)Themes: 1. Introduction: Fundamentals of Distribution Equilibrium2. Gas Chromatography 3. Liquid Chromatography 4. Other Analytical Separations Homework: Problems will be assigned throughout the semester as an aid in comprehending the course material. They will not be graded. Answers to the assigned problems will be discussed in the class.Quiz and Exams: Four quizzes will be given throughout the semester as an aid to review the course material periodically. Two exams will be included in the course. The midterm exam covers the first and second themes, and it will be a 2-h exam during October. The final one is a comprehensive exam, but it will emphasize the last two themes. Note that students are invited to submit suggested questions for the midterm and final exams. Group study: Research-oriented study on a specific topic related to separation. The topic will be given by the instructor. One group is composed oftwo students. The group study includes (1) a thorough review of the current state of the art on the research work related to the chosen topic and (2) a novel solution from the student group. The results from the group study will be shown as a group presentation: 20-min talk. Presentation date: November 30.Research Proposal: The topic of the proposal is on a separation technique. This topic can be related to the work from group study, but each student must submit a unique proposal. The proposal should present a novel idea that can be evaluated experimentally. The length of the proposal is about 1800 words. The final dual date: December 6, and no score will be given for a late submission. Grading: Homework:……………………………..0 points4 Quizzes…………………………….....20 points (5 points for each)Midterm Exam:………………………...80 pointsFinal Exam:…………………………….100 pointsGroup study:…………………………....40 pointsResearch Proposal:…………..………..60 pointsThe topics of group projects for choice:1. Diagnosis of brain-eating amoeba infections2. Quantitative detection of a cytokine in blood samples 3. An in-vivo device for monitoring soldiers’ potential exposure to chemical and biological warfare agents in military operations. 4. Rapid detection of HIV in blood samples5. Quantitative detection of Hg in fish6. Detection of prostate cancer7. Detection of single-nucleotide a single human cell 8. Real-time measurement of the level of a specific m-RNA in single cells 9. Whole-genome sequencing of a human fetus using a blood sample of the