PowerPoint PresentationSlide 2Slide 3Slide 4Slide 5Slide 6Slide 7Slide 8Slide 9Slide 10Slide 11Slide 12Slide 13Slide 14Slide 15Slide 16Slide 17Slide 18Slide 19Slide 20Slide 21Slide 22Slide 23Slide 2420 nmCharles Cao([email protected]), 226 Leigh hall.GrowthBio-analyticalApplicationsAssemblyPropertiesChemical SeparationsCHM 6154 (Fall, 2013)Instructor: Charles Cao ([email protected]), 226 Leigh Hall.Lectures: M, W, F, 7th Period (1:55 pm to 2:45 pm), 104 Leigh Hall Office hours: M, W, F, - 8th Period (3:00pm to 3:50 pm), or by appointmentWebsite: http://www.chem.ufl.edu/~cao/CHM6154/index.htmlRequirement: Strong background in calculus and thermodynamicsTextbook: Unified Separation Science by J. Calvin Giddings (John Wiley & Sons, INC) Reference: The Essence of Chromatography by Colin Poole (Elsevier)Themes: 1. Introduction: Fundamentals of Distribution Equilibrium2. Gas Chromatography 3. Liquid Chromatography 4. Other Analytical SeparationsHomework: Problems will be assigned throughout the semester as an aid in comprehending the course material. They will not be graded. Answers to the assigned problems will be discussed in the class.Quiz and Exams: Fourth quizzes will be given throughout the semester as an aid to review the course material periodically. Two exams will be included in the course. The midterm exam covers the first and second part of the themes, and it will be a 2-h exam during October. The final one is a comprehensive exam, but it will emphasize the last two parts of the themes. Note that students are invited to submit one or more suggested questions for the midterm and final exam.Group study: Reach-oriented study on a specific topic related to separation. The topic will be given by the instructor. One group is composed of two students. The group study includes (1) a thorough review of the current state of art on the research work related to the chosen topic and (2) a new and novel solution from the student group. The results from the group study will be shown as group presentation: 20-min talk. Presentation data: Dec. 1.Research Proposal: The topic of the proposal is on a separation technique. This topic can be related to the work from group study, but each student must submit a unique proposal. The proposal should present a novel idea that can be evaluated experimentally. The length of the proposal is about 1800 words. The final dual date: December 4, and no score will be given for a late submission.Grading: Homework:……………………………..0 points4 Quizzes……………………………....20 points (5 points for each)Midterm Exam:………………………...80 pointsFinal Exam:…………………………….100 pointsResearch Proposal:…………..…….…60 pointsGroup Study:…………………………...40 pointsTeachingDiscussionChemical Separations1. Fundamental knowledge2. Power of creativity in use of the knowledge that you have learnt.Goals1. I know the fundamentals of chemical separations2. I know the basic techniques in chemical separation3. I know how to use these techniques4. I know how to use the fundamental knowledge to improve these separation techniques1. Homework and class discussion 2. Four Quizzes (5 points each): during classes.3. Exams (Midterm: 80 points, and final: 100 points)A makeup exam for midterm exam is available (The highest point will be picked up). 5. Research-oriented study: 40 points4. Research proposal: 60 points How do we achieve the goals?Problem Solving and ResearchA scientific research activity:ObservationQuestions HypothesisExperimentsSummaryProblem solving: Questions HypothesisExperimentsSummary1. Understanding concepts and formulas 2. Logical Analysis Formal logic laws: (a) A event is determined by many parameters; (b) all the parameters have some sort of connection between each other. Scheme 1. A four-step method for problem solving1. Understand the question.2. Lay out all the parameters regarding the question.3. Use concepts and formulas to build connections between these parameters.4. Solve the question.Nature: A research paper cannot exist alone in an isolated manner; it must exist in a literature network in a “3-D” manner (the three dimensions are time, research field, and research group).How Can You Read?Levels of Understanding a research paper Level 1: Fully understand the general language: including all terminologies.Level 2: Fully understand the technical details: including the details of experimental and/or theoretical methods, and the details on how these technical methods were used in the generation of experimental and/or theoretical results.Level 3: Fully understand the structure of this paper: including the main scientific points, and the way that the main points are supported by the newly generated experimental or theoretical results. Do the arguments follow the general rules of scientific logic? Level 4: Advanced understanding of paper structure: Can you write a better paper if you have all the data from the paper?Level 5: Understanding of scientific value of the paper: Why was the paper published in a specific journal? Level 6: Understanding of authors: Which type of researcher are they in person? What did they really think during the paper writing?Content of part one Part 1. Introduction; Fundamentals of Distribution Equilibrium1. Chemical Separations: The Big Picture Classification and comparison of methods2. Fundamentals of Distribution Separations3. Separation Methods Based on Distributions in Discrete Stages Such as solvent extraction and distillation4. Introduction to Distribution Separations in chromatographic methods The plate theory, the rate theory; van Deemter's equationChemical Separations: The Big Picture (8/21/13)Chemical Separation is a central part of analytical chemistryAnalytical chemistry: What? and How many?The concepts we need to remember1. The essential feature of separations:2. Driving force for separative transport3. Limitations for separation4. Analytical and Preparative Separations5. Names for Chromatography techniquesWhat is Chemical Separation? (I)1. A complete separation of a mixture of chemical species:(a + b + c + d + e + …) (a) +(b) +(c) + (d) + (e) + …2. A partial separation of a mixture of chemical species:(a + b + c + d + e + …)(a) + (b + c + d + e + …)(a + b) + (c + d + e) + …3. The essential feature of separations:Components must be transported and redistributed