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UB BIO 329 - Review of Mendelian Genetics

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PowerPoint PresentationSlide 2Slide 3Slide 4Slide 5Slide 6Slide 7Slide 8The trait for medium-sized leaves in iris is determined by the genetic condition PP'. Plants with large leaves are PP, whereas plants with small leaves are P'P'. The trait for red flowers is controlled by the genes RR, pink by RR', and white by R'R'. A cross is made between two plants one with medium-sized leaves and pink flowers and one with large leaves and pink flowers. If they produce 320 seedlings, what would be the expected phenotypes, and in what numbers would they be expected? Assume no linkage. A plant with small leaves and white flowers was crossed with a plant with medium-sized leaves and pink flowers with the following results. Does this data fit Mendelian expectations for random segregation of the color gene? What about independent assortment of both genes?Medium pink 150Medium white 250Small pink 150Small white 250In the mouse, gene A allows pigmentation to be deposited in the individual coat hairs; its allele a prevents such deposition of pigment, resulting in an albino. Gene B gives agouti (wild-type fur); its allele b gives black fur.(a) Diagram the cross between a doubly heterozygous agouti mouse mated with a doubly homozygous recessive white mouse.(b) What would be the expected phenotypic ratio in the progeny? A further gene in mice is located on the X chromosome and codes for short ears. (a) Diagram the cross between a short-eared, agouti female and a black, normal eared male.(b) What would be the expected phenotypic ratio in the progeny?Chpt 4 Q 10In mice, there is a set of multiple alleles of a gene for coat color. Four of those alleles are as follows:C = full color (wild)cch = chinchillacd = dilutionc = albinoGiven that the gene locus is not sex-linked and that each allele is dominant to those lower in the list, diagram the crosses indicated below and give the phenotypic ratios expected from each.(a) wild (heterozygous for dilution) × chinchilla (heterozygous for albino)(b) chinchilla (heterozygous for albino) × albinoThe following coat colors are known to be determined by alleles at one locus in horses:palomino = golden coat with lighter mane and tailcremello = almost whitechestnut = brownThe following table gives ratios obtained in matings of the above varieties:Cross Parents Offspring1 cremello × cremello all cremello2 chestnut × chestnut all chestnut3 cremello × chestnut all palomino4 palomino × palomino 1/4 = chestnut 1/2 = palomino 1/4 = cremelloAssign gene symbols for the genetic control of coat color on the basis of these data. Diagram the last two matings. Chpt 4 Q 151) A newly discovered beetle species, lovebugs, have elytra (the hard shell covering the wings) color controlled by three loci. The B locus green color allele B is dominant to the blue allele b. The M locus has a dominant M allele that causes a metallic colored elytra; the recessive allele results in a dull background. The A locus has a dominant allele that confers white spots but only in the presence of the mm genotype at the M locus. The recessive aa genotype results in no spots. Eight young lovebugs were produced in a mating between a spotted green dull male and a blue metallic female with no spots. Their phenotypes were 3 metallic green, 2 dull blue, 2 spotted dull blue, and 1spotted dull green. What are the genotypes of the parents and the offspring?2) Imagine the two genes in your fly experiment. After the test cross, you found 210 flies were wild type at both loci, 176 flies had the mutant phenotype at both loci, and 64 flies were wild type at one locus and had the mutant phenotype at the other locus. How many map units are these loci apart from one another?3) Show a cross between an orange female and a black male cat. Show the genotypes of the parents and the potential genotypes and phenotypes of the offspring (remember this is a sex-linked locus where black and orange are codominant (calico) in females but males are only black or orange). What is the probability of getting a calico offspring from this cross?Suppose you isolated a new phenotype in mice which you name elmo, because it results in mice with reddish hair and an orange nose. True breeding stocks have been established where both males and females have reddish hair and an orange nose. In preliminary results of interbreeding elmo mice and wildtype mice, male mice seem more likely to have the elmo phenotype of reddish hair and an orange nose. Two hypotheses were proposed to explain these initial observations: The elmo allele is a recessive sex linked trait and therefore males are more likely to show the phenotype of the recessive allele.The elmo trait is a sex influenced trait, heterozygous males have the elmo phenotype but heterozygous females have wildtype coloring. Describe a reciprocal cross experiment to distinguish between these two hypotheses.What results would support hypothesis I?What results would support hypothesis II?Three recessive traits in garden pea plants are as follows: yellow pods are recessive to green pods, bluish seedlings are recessive to green seedlings, creeper (a plant that cannot stand up) is recessive to normal. A true-breeding normal plant with green pods and seedlings was crossed to a creeper with yellow pods and bluish seedlings. The F1 plants were then test crossed and the following results were obtained: 2,059 normal, green pods and seedlings 16 creeper, green pods, bluish seedlings 151 creeper, green pods and seedlings2,041 creeper, yellow pods, bluish seedlings 283 normal, green pods, bluish seedlings 157 normal, yellow pods, bluish seedlings 282 creeper, yellow pods, green seedlings 11 normal, yellow pods, green seedlings Construct a genetic map that describes the map distance between these three


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UB BIO 329 - Review of Mendelian Genetics

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