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How the Scientific Process gives you Fundamental Skills
- How to Gather information - How to Evaluate Sources of Info - How to Interpret Info
What is Science?
- Create new info - Build/ expand on prior knowledge - constantly changing - dissent and alternatives encouraged - A process of discovery that allows us to link isolated facts into a greater understanding
Sources of Uncertainty
Ignorance - We don't know enough Complexity - We don't understand how the parts work together
What is the Scientific Method?
-Techniques for investigating some observed phenomenon - acquiring new knowledge - or revision of previous knowledge
Scientific Method
-Observe -Define the Question -Gather Info. and Resources (observe) -Form Hypothesis -Formulate Predictions -Perform Experiment - collect data -Analyze Data -Interpret Data and draw conclusions - Publish Retest ( Frequently done)
Peer-Reviewed
Work has been read and evaluated by other members of the profession (and an editor) before being published -typically published by professionals (professors, institutions, and commercial publishers) for professionals ( students, experts, etc)
Hypothesis
Explanation for an observed phenomenon should demonstrate a causal relationship and/or a pattern you wish to know more about
Prediction
What you expect to find (often from deductive reasoning)
Hypotheses
-Must be testable (falsifiable)
Casual Relationship
Implies Mechanism
Correlation
Implies a relationship btw two events
Independent Variables
What you can control or vary, what you modify or manipulate
Dependent Variable
What you measure, responds to the changes you make
DRY MIX
DRY MIX
Mean
Average value of the sampled points - Add the values and divide by the total number of points
Median
The midpoint of all sampled points (sorted, take the one in the middle)
Mode
Most frequent occurrence among sampled points (the one that occurs most often within a dataset)
Subjective Terms
Comparing means can help to remove the ambiguity, but need to be interpreted with caution eg.) more, less, bigger, smaller - Difficult to evaluate
What is Biology
Study of living things
What causes variation among living things?
Genetics and environment * Genes and the environment can interact with each other
Biotic
Living Components - predators present - food
Abiotic
Non-living components - Sunlight -Wind - Temperature
Fundamental Properties of Life
-Growth and Reproduction -Ability to Respond - Ability to Evolve and Adapt (change over time) - Metabolism -Organized Structure -Organic Composition
Prokaryotes
Bacteria -small, single celled, DNA in single chromosome
Eukaryotes
-Plants -Fungi -Animals -Protists -Single or multicellular -membrane- enclosed organelles -DNA in multiple chromosomes
Cytoplasm
The cell substance between the cell membrane and the nucleus
Plasma Membrane
a microscopic membrane of lipids and proteins that forms the external boundary of the cytoplasm of a cell
Cell Wall
a rigid layer of polysaccharides lying outside the plasma membrane of the cells of plants, fungi, and bacteria. In the algae and higher plants, it consists mainly of cellulose.
Nucleoid (DNA)
irregularly-shaped region within the cell of a prokaryote that contains all or most of the genetic material, called genophore
Mitochondrion
- Found in both plant and animal cells -an organelle found in large numbers in most cells, in which the biochemical processes of respiration and energy production occur.
Chloroplast
in green plant cells) a plastid that contains chlorophyll and in which photosynthesis takes place. - only in plant cells CO2 + H20 = O2 + C6H12O6 (Carbohydrate)
Chemosynthesis
Creates sugars from inorganic chemicals, CO2 and O2 Used by bacteria in ecosystem with no light - ocean depths CO2 + O2 = C6H12O6 ( Carbs) + H20 + S (Sugar)
Cellular Respiration
Glucose broken down - produces CO2 and H2O - Releases energy thats required for organism growth and reproduction - Happens in the Mitochondrion O2 +C6H12O6 = C)2 + H2O + Energy (ATP)
Anaerobic Respiration
Cellular respiration without O2 - works without O2 -Yields less energy - used to make beer C6H12O6 = CO2 + H2O + Ethanol + Some ATP
Endoplasmic Reticulum (ER)
- Smooth (no ribosomes) Makes lipids, also helps protect the body from compounds and toxins that can harm us such as alcohol, antibiotics, etc) - Rough (ribosomes attached) - ribosomes = protein production - fold and package proteins
Golgi Apparatus
Protein Processing and Delivery System - Bud off of the golgi app. and delivers to the cytosol and used throughout the body
Plant Cells
- Chloroplasts (photosynthesis) - Cell Wall (Structure/Protection) -Vacuoles - Nutrient storgage - Waste Management - Predator Deterrence (Toxin Storage) - Reproduction (Pigment Storage) - Support (Osmotic Balance
How Do Cells Grow?
Growth (add more cells) - Get Bigger Maintenance (add more cells) - Replace damaged cells - Tissue repair, liver regeneration Simple Cell Division - Genetically Identical Offspring
Asexual Reproduction
Simple Cell Division Genetically identical offspring
Sexual Reproduction
Requires 2 individuals - gametes produced to form a Zygote - Genetically diverse offspring
Gamete
a mature haploid male or female germ cell that is able to unite with another of the opposite sex in sexual reproduction to form a zygote
Zygot
a diploid cell resulting from the fusion of two haploid gametes; a fertilized ovum
DNA
Deoxyribonucleic Acid (DNA) is the heritable component - Helix in shape, made of 2 stands, bound together by hydrogen bonds Contains 4 base-pairs - Adenine, Thymine, Guanine, Cytosine
How Many Pairs of Chromosomes do Humans Have?
23 pairs Males XY Females XX
Interphase
Replication of the DNA
Prophase
Chromosomes condense
Metaphase
Chromosomes align along the metaphase plate
Anaphase
Sister chromatid split and are pulled to opposite ends of the cell
Telophase ( and Cytokinesis)
The Cell split into two cells: each containing an identical set of chromosomes
Mitotic Division
Creates two genetically identical (daughter) cells from one original (parent) cell helps with injuries, and normal cell turnover ( tissue repair)
Cancer
Uncontrolled Cell Division - cells are dividing faster than they should be
Benign
Will NOT invade other tissues and will not metastasize - may grow large so at times will need to be remove before the encroach on other organs (e.g brain, intestine)
Malignant
CAN INVADE other tissues and implies the ability to metastasize (move to other parts of the body) - Typically faster growth
Why is Curing Cancer Complex?
- Many result from cel-cycle control problems - Cells are dividing faster than they should and moving to other areas - Mistakes are made in creation of cells due to rapid division
Meiosis
a type of cell division that results in FOUR daughter cells each with half the number of chromosomes of the parent cell
Mitosis
a type of cell division that results in TWO daughter cells each having the same number and kind of chromosomes as the parent nucleus, typical of ordinary tissue growth problems with it - Cancer - Cell cycle under TIGHT CONTROL - NOT USED FOR HUMAN REPRODUCTION
How Do We Keep Chromosome Numbers Constant?
Meiosis - Reduces the amount of genetic material in the cell by half - contains ONE copy o each gene instead of TWO like you would see in the rest of the body
How does Sex provide Various Offspring?
Each child is created by a separate zygote Therefore, they are genetically related but also genetically distinct from one another - genetic material comes from 2 ind vs. just 1 - Ind. assortment in gamete production - Recombination (swapping alleles btw homologous chromosome…
Genotype
What variants of a gene are in your cells
Phenotype
The physical, biochemical, and physiological makeup of an ind. as determined both genotypes and the environment
Evolution
Change in the properties of groups of organisms over the course of generations
Requirements of Evolution
Phenotype vs. Genotype Environmental effects on phenotype Heritable Components Mutations Natural Selection Sexual Selection
Darwin's 4 Postulates
1. There is variation in the population 2. The variation has an underlying genetic component 3. There is competition (not all ind. will survive and reproduce equally) 4. Ind. with alleles for a certain trait will be better (and/or worse) than other individuals in the pop. and this with…
Selection
Directional - one trait is favor over another Overdominance - heterozygote has a higher fitness Underdomiance - Heterozygote has lower fitness
Directional Selection
Removes one particular extreme phenotype
Adaptations
Inherited structure, functions, behaviors - Give survival and reproductive advantages
Natural Selection
Most fit leave more offspring - their adaption becomes more common Less fit have fewer offspring, their adaption becomes less common
Stabilizing Selection
Removes extreme phenotypes
Disruptive Selection
Removes medium-sized phenotypes
Heterozygote
Ind. with 2 different alleles for a given gene Occurs when - mating with ind. less similar to you -Diseases and Major histocompatability complex (MHC)

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