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Fluid mosaic model
Proposed by Singer and Nicolson, describes the structure of the plasma membrane as a mosaic of components including phospholipids, cholesterol, proteins, glycoproteins, and glycolipids
Phospholipids
Create a hydrophobic barrier between the cell and exterior
Phospholipid structure
Hydrophilic head and two fatty acid tails, 1 saturated 1 unsaturated. Makes the tail hydrophobic
Desaturation and temperature
Fatty acid desaturation(C=C bond) yields lower freezing point
Protein functions
Cell recognition, signal reception and transport
Plasma membrane components
Phospholipid-main component Cholesterol-attached between phospholipids and between the two phospholipid bilayers Integral proteins-embedded within the bilayers Peripheral proteins-on the inner and outer surface of the bilayer Carbohydrates-attached to proteins I the outside membrane l…
Amphiphilic
Molecule possessing a polar(charged) and nonpolar(uncharged) area capable of interacting with both hydrophilic and hydrophobic environments
Passive transport
Moves materials along their concentration gradient, no energy expended
Facilitated diffusion
Moved substances down their concentration gradients by using proteins as channels
Carrier proteins
Move molecules across cell membranes by changing shape
Osmosis
Passive move rn of water across cell membranes along its concentration gradient
Tonicity
Measurement of the concentration of the extracellular fluid that affects movement of water across the membrane (hypotonic, isotonic, hypertonic)
Hypertonic
Water moves out through membrane, leaving structure shriveled
Isotonic
Water flows evenly in and out of the structure
Hypotonic
Water moves into the structure through the membrane, filling it up
What way does water always move?
Higher concentration to lower concentration across a membrane
What does lower concentration imply?
More material is dissolved in the water
Active transport
Method of transporting material that requires energy
Electrochemical gradient
Gradient produced by the combined forces of an electrical gradient and a chemical gradient
What is the overall charge of a cells interior
Negative (3 Na+ ions out, 2 K+ ions in) cells accumulate potassium and transport sodium out
Because of the negative charge..
There is a greater pull for positive ions
Primary active transport
Uses energy (often ATP) to push material against its concentration gradient, maintaining concentration difference across membranes. Ex. 3 Na+ ions out for each 2 K+ ions in, maintains cells negative interior charge
Uniporter
Carries one specific ion or molecule
Symporter
Carries two different ions in the same direction
Antiporter
Carries two different ions but in different directions
Secondary active transport (co-transport)
Uses a gradient generated by primary active transport to enhance the movement of a second substance across the membrane
Endocytosis
Movement of material into the cell by changes in the cell membrane
Bulk transport
Movement of macromolecules in or out of a cell. Two types-exocytosis and Endocytosis
Phagocytosis
Large particles such as cells or relatively large particles are taken in by a cell
Pinocytosis
Imports molecules that the cell needs from the extracellular fluid
Receptor-mediated Endocytosis
Involves the use of specific binding proteins in the plasma membrane for specific molecules or particles Involves an invagination of the cell membrane
Clathrin
Stabilizes the membrane
Familial hypercholesterol
Folks lack the LDL receptor, cholesterol can't be removed from the blood
Exocytosis
Release of material from a cell by changing the cell membrane
Producers
Convert sunlight into biomass
Consumers
get their energy by consuming the producers
Photosynthesis
Light energy generates ATP and NADPH to convert CO2 to biomass
ATP
Chemical energy
NADPH
Electron source for biosynthesis
Oxidation
Removal of electrons from a compound
Photosynthesis equation
6CO2 + 6H2O + light energy --> C6H12O6 + 6O2
Calvin cycle equation
C6H12O6 + 6O2 --> 6CO2 + 6H2O + energy (ATP and NADPH)
Breaking chemical bonds (catabolism)..
Of glucose releases energy
How much ATP is needed per glucose oxidized
36-38
Complete oxidation of glucose..
Yields CO2
Metabolic pathway
Series of linked reactions that take a substrate and convert it into a product
Anabolic pathway
Converting a substrate into a more complex structure (requires energy)
Catabolic pathway
Converts substrate into less complex structure (tends to release energy)
Potential energy
Stored energy
Kinetic energy
Energy of movement or activity
Enthropy
Level of disorder or randomness in a system
Activation energy
Amount of energy required to start the reaction
First law of thermodynamics
Amount of energy in the universe cannot change, energy cannot be created or destroyed
Second law of thermodynamics
Energy transfers are inefficient therefore, in every energy transfer some energy is "lost" (released in an unusable form-generally heat)
Enzyme
Protein catalysts-facilitate reactions without being destroyed in the process. Reduce amount of activation energy required to begin a reaction

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