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Vitamin
organic essential nutrients required in tiny amounts
*Bloavallavillty
rate and extent to which nutrient is absorbed and used Vitamins can be damaged by light, oxygen, heat and washing. Refrigeration slows deterioration as does cooking minimum time in minimum water. Preparation method can be important.
Precursor
substance that preceeds others – some precursors can be converted to an active vitamin inside the body
Fortification
Adding nutrients to foods to prevent deficiencies or promote health
Enrichment
adding nutrients to restore those lost in processing
Vitamin Functions: Coenzymes, Antioxidants
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Coenzymes
that increase activity of enzymes – B vitamins are especially important in extracting energy in Krebs cycle
Antioxidants
prevent cellular damage by preventing free radical formation
Water-Soluble Vitamins
carried freely in watery blood and excesses are excreted by kidneys, thus are not very toxic, but excess can cause problems. These are carried in the blood stream to the liver Vitamins come from a varied food supply – especially fruits & vegetables.
Toxicity is dose related response
more is not always better – fat-soluble vitamins and minerals can be toxic at high doses with no good excretion route
Fat soluble vitamins
carried initially in chylomicrons in the lymph system till protein carriers are attached.
Water Soluble Vitamins
include 8 B vitamins and Vitamin C: B vitamins serve as coenzymes in energy metabolism (TCA cycle and Electron Transport Chain) so deficlencles lead to a lack of energy
Thiamine
coenzyme in energy release from nutrients - nerves and muscle & in synthesis of neurotransmitters for nerve cells
Beri-Beri
Deficiency disease discovered with advent of rice polishing Also involved in Warnike-Korsakoff syndrome in alcoholics when alcohol decreases absorption of thiamine No reported toxicity Source - pork, whole grains, legumes - Leaches into cooking water
Riboflavin (Coenzyme)
coenzyme - energy release from nutrients – all body cells Deficiency – inflammation of membranes especially eyes and mouth Source – milk, whole grains, green vegetables UV light destroys but not heat – pasteurized milk is packaged in opaque cartons to protect riboflavin
Niacin
coenzyme in energy transfer - lowers cholesterol, functions in glucose and fatty acid metabolism Body can make it from tryptophan Deficiency – pellagra (4 D’s – diarrhea, dermatitis, dementia, death) was common in South till WW 1due to high corn diets deficient in niacin Toxicity – nia…
Biotin
coenzyme that carries CO2 in TCA cycle Deficiency – rare can be induced by raw egg whites which have Avidin – causes nausea, hair loss, lethargy Source – egg yolks & widespread in foods No reported toxicity
Panothenic acid
part of coenzyme A - crossroads compound in metabolic pathways Deficiency – rare – involves general failure all body systems Sources - widespread in meats, cereals, vegetables Relatively nontoxic
Vitamin B6
coenzyme in amino acid metabolism, hemoglobin and DNA synthesis – works with more than 100 enzyme systems Deficiency – depression & confusion – hastened by high protein diet making needs more Toxicity – only with supplements – causes neurological damage Source – meat, fish, poultry, ve…
Folate (folic acid)
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