PHARMACOLOGY OF ANTIDEPRESSANTS AND MOOD STABILIZERS Philip G Janicak MD Professor of Psychiatry Rush University I II III IV Introduction Diagnostic Indication for Antidepressants A Major Depressive Disorder Mood Behavior Cognitive B Dysthymic Disorder C Bipolar I Disorder Depressed or mixed episode D Bipolar II Disorder Depressed or mixed episode E Cyclothymic Disorder F Other Disorders Schizoaffective bipolar or depressed type Due to a General Medical Condition Substance induced Pharmacodynamics of Antidepressants A Serotonin 5 HT SSRI e g fluoxetine SARI e g nefazodone B Catecholamine NE DA NDRI e g bupropion SNRI e g reboxetine C Serotonin Catecholamine TCA e g imipramine MAO I e g phenelzine SSNRI e g venlafaxine NaSSA e g mirtazapine Adverse Effects and Drug Interactions of Antidepressants V Treatment Strategy for Major Depression VI Diagnostic Indications for Mood Stabilizers A Bipolar Disorder General Considerations B VII Treatment of Bipolar Disorder Pharmacodynamics of Mood Stabilizers A Lithium B Anticonvulsants Valproate Carbamazepine Others C Novel Antipsychotics Olanzapine Others VIII Adverse Effects Pharmacokinetics and Drug Interactions and of Mood Stabilizers IX Treatment Strategy for Acute Mania X References
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