MIT
7 03 -
Lecture Notes
Unformatted text preview:
View Full Document
Oncogene — dominant gain-of-function mutations promote cell transformation Tumor suppressor gene — recessive, loss-of-function mutations promote cell transformationImages removed due to copyright reasons.growth checks (DNA synthesis) S G1 G0 G2 Extracellular control signals Intracellular quality control Daughter cells M (Mitosis) Figure by MIT OCW.Cell cycle in S. cerevisiae Mother cell Growth Spindle pole body duplication Spindle formation Chromosome segregation; Cytokinesis M G1 G2 S Daughter cell START Bud emergence DNA replication Nuclear migration nuclear division Figure by MIT OCW.A Genetic Screen for Cell Cycle Mutants Figure by MIT
View Full Document
Unlocking...