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Oncogene dominant gain of function mutations promote cell transformation Tumor suppressor gene recessive loss of function mutations promote cell transformation Images removed due to copyright reasons Daughter cells Extracellular growth control signals G0 Intracellular quality control checks M Mitosis G1 G2 S DNA synthesis Figure by MIT OCW Cell cycle in S cerevisiae Mother cell Cytokinesis Daughter cell Chromosome segregation nuclear division Growth G1 M START Spindle pole body duplication Spindle formation S G2 Bud emergence DNA replication Nuclear migration Figure by MIT OCW A Genetic Screen for Cell Cycle Mutants Figure by MIT OCW


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MIT 7 03 - Lecture Notes

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