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cell
the smallest functional structure in a living organism; a human has 100 trillion
organelles
structures within cells that perform specialized functions; EX: nucleus, mitochondria, ribosomes
tissues
collection of similar cells that perform specialized functions
epithelial tissue
cells that form linings and coverings; ex: skin
connective tissue
cells that hold together, protect, and support organs; ex: bone, fat
organs
collection of tissues that perform a specific function
systems
collection of organs that work together to perform a major function
homeostasis
body trying to maintain a steady state (equilibrium)
Respiratory System
-main function is for exchange of oxygen and carbon dioxide -lungs: enable body to exchange gases, mainly oxygen and carbon dioxide -nose, pharynx, larynx, trachea, bronchi, lungs
Cardiovascular System
-main function is to circulate blood throughout the body -delivering oxygen, food, water and taking away carbon dioxide and waste products -heart, major veins and arteries, blood
artery
(red) delivers oxygen rich blood to cells (high pressure)
vein
(blue) takes away waste and carbon dioxide (low pressure)
Lymphatic System
-helps maintain fluid balance, absorb many fat-soluble nutrients, and defends the body against diseases -lymph nodes, lymphatic fluid, white blood cells, spleen, thymus
lymph nodes
inflame to respond to fight a problem, immunity support
Urinary System
-main function is elimination of salts, water, and wastes; maintenance of fluid balance -kidneys, bladder -body filters all of its blood 300x per day
kidneys
filter unneeded substances from blood and help maintain proper fluid balance
bladder
stores urine until elimination
kidney stress indications
hurts to pee, pee color
dehydration
whole body stressor
hydration test
skin release test, skin does not pop back "pinch test"
Muscular System
enables movement to occur, and provides support and protection -muscles
Skeletal System
-bones provide support, movement, and protection -bones also store certain minerals and PRODUCE RED BLOOD CELLS
Nervous System
-main function is thought processes, regulation and coordination of many body activities, detection of changes in external and internal environments -(email system) neurons in the brain, spinal cord, and throughout the body transmit information and responses by electrical and chemical si…
neurons
nervous system cells
Endocrine System
-main function is regulation and coordination of many body activities including growth, nutrient balance, and reproduction -organs and tissues that produce hormones -thyroid, hormones
thyroid
influences metabolism (how many calories you need to stay alive)
hormones
determine sex, chemical messengers that regulate body processes and responses
Integumentary System
-main function is for protection, immunity, regulation of body temperature, and vitamin D synthesis -skin, hair, and nails
Reproductive System
-main function: produce children -only system we can live without -gonads and genitals
Digestion System
-main function is digestion and absorption of nutrients -mouth, salivary glands, esophagus, stomach, intestines, pancreas, liver, gallbladder -GI Tract, Bioavailability
GI Tract
muscular tube that extends from the mouth to the anus
bioavailability
extent to which digestive tract absorbs nutrients and how well the body uses them
mouth
where digestion begins -mechanical & chemical digestion
mechanical digestion
biting and grinding actions break and mash food into smaller pieces
chemical digestion
saliva mixes and lubricated food -salivary amylase and lipase begin breakdown of starch and fat
taste buds
specialized sensory structors on the tongue and in the lining of the mouth and throat -5 tastes
five tastes
umami, sweet, sour, salty, bitter
smell
chemicals in food become airborne and stimulate nasal passages, contributing to sense of taste
peristalsis
muscular contractions that move small amounts of foods and beverages through intestinal tract
stomach
-gastroesophageal sphincter, chyme, mucus, pyloric sphincter -ulcers -BRAT -food is here for 7-8 hours
gastroesophageal sphincter
-located at the end of the esophagus -controls opening and closing of the stomach
chyme
mixture of gastric juice and partially digested food, very acidic
mucus
layer of mucus protects stomach from acid
ulcer
stomach mucus is not maintained, acid burns stomach, often bleed, blood in stools, caused by h.pylori
BRAT diet
banana, rice, apples, toast
pyloric sphincter
controls rate of chyme release into small intestine
Small Intestine
-where most nutrients are digested and absorbed -duodenum, jejunum, ileum
vestigial
an organ we do not need
Liver
-processes and stores many nutrients -500 functions -makes cholesterol and bile
Gallbladder
stores bile that aids in fat digestion
Pancreas
produces and secrets many digestive enzymes and bicarbonate ions
Absorbing Nutrients
-villi, absorptive cells
villi
tiny projections that line the small intestine
absorptive cells
remove nutrients from chyme and transfer them into blood or lymph
Large Intestine
-absorption of water and minerals -colon and rectum -feces, rectum
feces
form as chyme becomes semisolid
rectum
lower part of the large intestine where feces are stores
macronutrients
provide energy to the body
the body uses proteins to make or function as...
-new cells and many components of cells -structures such as hair and nails -enzymes -lubricants -clotting compounds -antibodies -compounds that help maintain fluid and pH balance -certain hormones and neurotransmitters -energy source (minor, under unusual conditions)
structural proteins
-are in cartilage, ligaments, and bones (COLLAGEN) -are in hair, nails, and skin (KERATIN)
contractile proteins
enable us to move
clotting proteins
needed for blood clotting
hormone proteins
chemical messengers that regulate body processes and responses (insulin and glucagon)
enzymes (nearly all enzymes are proteins)
speed up (catalyze) chemical reactions without becoming part of the products
neurotransmitters
-proteins -send signals from one nerve to another
transport proteins
oxygen and many nutrients are transported in blood by special proteins, such as ALBUMIN
amino acids
-monomer of protein -20 different amino acids in human proteins
essential amino acids
cannot be made by the body, must be supplied by the diet (9 of the 20)
nonessential amino acids
can be made by the body (11 of the 20)
legume
-plants that produce pods with a single row of seeds -high protein, low fat, low sugar -soybeans, peanuts, lentils, beans
high-quality protein (complete protein)
-contains all 9 essential amino acids in amounts that support growth -animal products, quinoa, processed soy, rice & beans
low-quality protein (incomplete protein)
-lacks or has inadequate amounts of 1 or more of the essential amino acids -most plant foods and gelatin
Sickle Cell Anemia
if DNA code is faulty, the wrong amino acid may be inserted into a protein, causing detrimental effects such as defective hemoglobin -inherited condition that affects red blood cells
denaturation
altering a protein's natural shape and function by exposing it to various conditions including heat, alcohol, acid, and physical agitation -heat and raw eggs -acidic lemon juice curdles milk -hydrochloric stomach acid -whipping foods
Protein Digestion and Absorption
-stomach: denature proteins with stomach acid and partial digestion by pepsin -small intestine: further digestion as the pancreas secretes protein-splitting enzymes, including trypsin and chymotrypsin -small intestine cells: final digestion occurs within the absorption of the cells -…
albumin
protein that transports oxygen and many nutrients through the blood
where is protein absorbed?
small intestine
protein turnover
breaking down old an unneeded proteins into amino acids and recycling the amino acids
amino acid pool
amino acids that have not been incorporated into proteins yet
endogenous amino acids
amino acids from the amino acid pool
exogenous amino acids
amino acids from dietary sources
positive nitrogen balance (when protein needs increase)
-growth -pregnancy, lactation -recovery from illness/injury -increased levels of the hormones insulin, testosterone, and growth hormone -resistance exercise
nitrogen equilibrium
healthy adult meets protein and energy needs
negative nitrogen balance
-inadequate protein intake or digestive diseases that interfere with protein absorption -increased protein losses resulting from certain kidney diseases or blood loss -bed rest, fever, injuries, burns -increased secretion of thyroid hormone or cortisol
complementary protein
rice and beans
protein deficiency
-uncommon in the US -may occur in: elderly, low-income, alcoholics, anorexia nervosa, intestinal tract disorders
Kwashiorkor disease
-adequate energy intake, but low intake of high-quality proteins -edema (swelling) -> boy with indent on his feet
marasmus
-starvation- extreme weight loss, stunted growth -not enough calories or protein -protein therapy
allergy
inflammatory response resulting when body's immune system reacts inappropriately to a substance that is typically harmless
allergen
the offending substance
common signs of food allergies
hives -swollen itchy lips -skin flushing -scaly red skin (eczema) -difficulty swallowing -wheezing and difficulty breathing -abdominal pain, vomiting, diarrhea
common food allergies
-protein rich foods: cows milk, eggs, peanuts, wheat, soybeans, fish & shellfish -non-protein foods: food dies, sulfites added to wines, potatoes, shrimp
treatments to food allergies
-avoid them -epi pen= epinephrine
how are carbohydrates made?
through photosynthesis
simple carbohydrates monomer
monosaccharide (sugar)
glucose
-primary energy source -"blood sugar" -dextrose
fructose
-fruit sugar -levulose
galactose
-part of milk sugar
disaccharides
sugar comprised of two sugar molecules
maltose
glucose + glucose
sucrose
glucose + fructose
lactose
glucose + galactose
table sugar (sucrose)
-made from sugar cane or sugar beets -refinement strips away vitamins and minerals
complex carbohydrates monomer
polysaccharides
polysaccharides
more than or equal to 10 monosaccharides bonded together -storage form of carbohydrates in plants and animals -structural component of plants in stems and leaves
starch
-storage form of carbohydrate in plants -mainly in seeds, roots, and tubers
glycogen
-storage form of carbohydrate in humans and other animals -stored primarily in liver and muscles
fiber
-most forms are complex carbohydrates that humans cannot digest -insoluble: -soluble:
why are Americans so overweight?
SUGAR
insoluble fiber
-cellulose/hemicelluloses -increases fecal bulk and speeds fecal passage through GI tract -all plants, wheat, rye, brown rice, vegetables -lignin
soluble fiber
pectins, gums, mucilages, and some hemicelluloses -fills you up -delays stomach emptying, slows glucose absorption, can lower blood cholesterol -apples, bananas, citrus fruits, carrots, oats, barley, psyllium seeds, beans, and thickeners added to foods
lignin
-insoluble fiber -increases fecal bulk, may ease bowel movements -whole grains, wheat bran
whole grain
-the intact, ground, cracked, or flaked, seeds of cereal grains -must contain: fiber-rich BRAN, starchy ENDOSPERM, oily GERM
digestion of carbohydrates
-mouth: salivary amylase digests some starch -stomach: acid inactivates salivary amylase -small intestine: main cite for carbohydrate digestion and absorption -liver: absorbed monosaccharides travel to the liver -large intestine: some soluble fiber fermented -rectum: very little carb…
digestion
breaking down of foods (to monomers)
absorption
the taking in of nutrients from the food
what happens after eating carbohydrates?
-insulin is released from the pancreas: enables glucose to enter cells, enhances production/storage of fat, glycogen, and protein, and decreases hunger
what is the best source of energy for your body?
carbohydrates
what happens when you don't eat carbohydrates?
-blood glucose decreases and the pancreas releases glucagon, which stimulates glycogenolysis and lipolysis
glycogenolysis
-glycogen break down, releases glucose into the blood (faint, tired)
lipolysis
-breakdown of triglycerides (fat) for energy
ketosis
-condition that occurs with very high blood ketone bodies -unconsciousness or death may occur
ketone bodies
-form as a result of incomplete fat breakdown: poorly controlled diabetes, fasting or starving, low-carb high-protein diet -used by certain cells for energy
hypoglycemia
-abnormally low blood glucose levels -blood glucose is too low to provide cells with energy
reactive hypoglycemia
-blood glucose drops after eating highly refined carbohydrates, going w/o eating -pancreas responds to the carb intake by secreting excess insulin
diabetes mellitus
group of serious chronic diseases characterized by abnormal glucose, fat, and protein metabolism
glycemic index (GI)
method of classifying carbohydrate-rich food by comparing the rise in blood glucose after eating a portion of food that contains easily-broken down carbohydrates
glycemic load (GL)
grams of carbohydrates in a serving of food multiplied by the food's glycemic index
things that alter GI and GL
things that alter GI and GL
high fructose corn syrup composition
-made from corn -55% fructose, 45% glucose
why is high fructose corn syrup so heavily used?
it's cheap, it mixes easily, extends shelf-life by 20%, tastes sweeter, prevents freezer burn, makes baked products brown better, results in soft textures
what are the problems with high fructose corn syrup?
link to obesity, (doesn't work with insulin, doesn't signal leptin), higher levels fatty liver disease, it causes flatulence and diarrhea: your body does not know what it is, fructose malabsorption, metabolic syndromes, mercury, increases triglyceride levels, increases dental activities, …
types of lipids
fatty acids, triglycerides, phospholipids, cholesterol
insolubility of fat
-insoluble in water: problem because most of your blood is water, how are you going to move the fat?
America's lipid intake
#2 latest country (33% of average American diet) Mexico is #1
major functions of lipids in the body
-providing and storing energy (fat) -maintaining cell membranes -producing certain hormones -insulating the body against cold temperatures -cushioning the body against bumps and blows -contributing to body contours -absorbing fat-soluble vitamins and phytochemicals -contribute t…
triglycerides
-composed of 3 fatty acids attached to a glycerol backbone -95% of lipids in the body and foods
using triglycerides for energy
-adipose cells break down triglycerides into fatty acid and glycerol molecules before releasing them into the bloodstream -liver can convert glycerol to glucose for another energy source -high kcal
sterols
carbons arranged in rings, more complex than triglycerides and phospholipids -cholesterol is most well known
functions of cholesterol
the body uses cholesterol to make: vitamin d, steroid hormones (estrogen and testosterone), bile -makes brain work and helps with eyes
trans fats
-unsaturated fats with at least 1 trans double bond rather than the more common cis double bond -BAD, they collect around the heart artery, heart disease (illegal in some places like New York) -raise blood cholesterol levels, increase risk of heart disease
foods highest in cholesterol
animal products: egg yolk and liver
hydrogenation
-process that adds hydrogen atoms into liquid vegetable oils; making it stable so it will not spoil as easily -goes to the arteries of the heart -BAD
partial hydrogenation
-not all double bounds are hydrogenated -body reacts the same -BAD -accumulates against artery, hardens in arteries like plaque on teeth
saturated fats
BAD FOR YOUR HEART -trans fats -hydrogenated fats
essential fatty acids
cannot be made in the body -used to make several important compounds in the body -2 types are: alpha-linolenic acid (omega3-DHA and EPA) and liolenic acid (omega6-AA) -precursors (help to form) of prostaglandins
good fats
monounsaturated and polyunsaturated -olive oil
bad fats
saturated fats -safflower oil, canola oil, grapeseed oil

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