Front Back
Central Nervous System (CNS)
all parts of the nervous system enclosed in bone
Peripheral Nervous System (PNS)
all parts of the nervous system external to brain and spinal cord
Autonomic Nervous System
has 2 categories; sympathetic and parasympathetic
Somatic Nervous System
skeletal nerves
sympathetic
is the spinal cord only and controls fight/flight responses
parasympathetic
is the cranial nerves and spinal cord and is dominant after the stressor
Spinal Cord
dorsal vs. ventral root
Dorsal Root
Dorsal Root
Ventral Root
Motor nerves (ab side)
Meninges
Dura Mater, Arachnoid, Pia Mater
Dura Mater
tough, flexible, outer layer (hard mother)
Arachnoid
(spider-web) middle layer. Subarachnoid space- filled with CSF
Pia Mater
inner, soft layer
3 ways to slice the nervous system
Sagital, Horizontal, Coronal
Sagital
perpendicular to ground when facing body, midsaggital divides the brain into two halves
Horizontal
parallel to the ground
Coronal
perpendicular to the ground when facing side
Olfactory
I. Sensory
Optic
II. Sensory
Oculomotor
III. Motor
Trochlear
IV. Motor
Trigeminal
V. Both
Abducens
VI. Motor
Facial
VII. Both
Vestibulocochlear
VIII. Sensory
Glossopharyngeal
IX. Both
Vagus
X. Both
Spinal Accessory
XI. Motor
Hypoglossal
XII. Both
3 Parts of the Brain
Cortex, Brainstem, Cerebellum
Cerebral Cortex
a sheet of neural tissue that is outermost to the cerebrum
Cerebral Cortex
a sheet of neural tissue that is outermost to the cerebrum
Cerebellum
Dedicated to movement
Brainstem
Medulla, pons, midbrain. Vital to life, not personality
The 4 Lobes of the Brain
Parietal, Frontal, Occipital, Temporal
Temporal Lobe
MEMORY AND HEARING
Occipital Lobe
VISION
Parietal Lobe
TOUCH, body awareness
Frontal Lobe
DECISION MAKING
Sylvian Fissure
Horizontally separates temporal lobe
Central Sulcus
Laterally separates the frontal and parietal lobes
Calcarine fissure
divides the occipital lobe in half
Precentral gyrus
Frontal; Motor
Postcentral gyrus
Parietal; Sensory
Ventricular System
Series of chambers filled with cerebrospinal fluid (CSF)
Cerebrospinal Fluid (CSF)
two main functions: acts as shock absorber, provides an excange medium between blood and brain.
Choroid plexus
stringy, makes CSF
4 Ventricals
2 lateral, 1 third, and 1 fourth
Neurons
Nerve cells, primary sites for electrochemical communication that will eventually translate into behavior
Glial Cells
10 to 1 ratio. Involved with Cancer. Neural transmission and structure support
Parts of the Neuron
Cell body, dendrites, axon, axon terminals
Axons
send electrical signals.
Axon Terminals
site of neurochemical release.
Dendrites
receptors which receive information
4 Kinds of Glial Cells
astrocyte, Microglia, Oligodendrocytes, Schwann Cells
Astrocyte
star shaped. Receive neuronal input and monitor activity. Get information from the neurons. Don't know how they communicate with neurons. Receive information from capillaries and neurons.
Microglia
small cells that remove debris from injured cells. Clean up crew. Injuries
Oligodendrocytes
glial cells that form myelin sheath in the CNS
Schwann Cells
Provide myelin to cells in the PNS
3 structural types of neurons
- Multipolar Neurons - Bipolar Neurons - Monopolar Neurons
Multipolar Neurons
possesses a single axon and many dendrites. constitute majority of the neurons in the brain. dendrites connected to cell body and axon.
Bipolar Neuron
detect and signal changes within the nervous system. dendrites connected to axon and cell body
Monopolar Neuron
Two axons, dendrites only connected to axon. Rapid decision making Bipolar Neuron monopolar neuron multipolar neuron
3 Functional Types of Neurons
- Motor Neurons - Sensory Neurons - interneurons
Motor Neurons
contact muscles or glands
Sensory Neurons
respond to environmental stimuli, such as light, odor, or touch.
Interneurons
receive input from and send input to other neuro
The Neuron at Rest
resting potential kept by Pottasium (K) average resting potential= -60 mV K channels are always open to allow K to come into the cell K moves to negative interior of the cell due to electrostatic pressure; K diffues out of the cell when excess K inside
The Neuron in Action
if enought Na flows into cell to make it more positive and reach threshold (-40), action potential will occur an action potential causes Na gated channels to open and allows Na to flow into the cell making it more positive until it reaches about +40 (depolarization) at +40, gated K chan…
Importance of Myelin Sheath for Neurons in action
axons work best for action potential because the fat that covers the axons keeps the current from dissipating or back-firing. insulates and speeds conduction
hyperpolarization
is an increase in membrane potential, caused by inhibitory messages, which puts it farther away from zero.
depolarization
is a decrease in membrane potential caused by excitatory messages, bringing it closer to zero.
Excitatory postsynaptic potential (EPSP)
produces a small, local depolarization, pushing cell closer to threshold
Inhibitory postsynaptic potential (IPSP
produces a small hyperpolarization, pushing cell farther from firing; occurs when Cl- entering the cell
Temporal Summation
Summing of potentials that arrive at the axon hillock at different times; the closer together in time they arrive, the greater the summation and possibility of action potential
Spatial Summation
Summing of potentials that come from different parts of the cell; if overal sum of EPSPs & IPSPs can depolarize the cell at the axon hillock, an action potential will occur
Ligands
Fit receptors & activate or block them; two types
Endogenous Ligands
neurotransmitters and hormones
Exogenous Ligands
drugs and toxins from outside the body
Effects of ligand-binding
Agonist, Antagonist, or Inverse Agonist
Agonist
Initiates the normal effects of the receptor
Antagonist
Blocks the receptor from being activated by other ligands
Inverse Agonist
Initiates an opposite effect of the receptor's normal function
Ionotropic Receptors
Open when bound by transmitter (ligand-gated channel)
Metabotropic Receptors
Recognize the transmitter but instead activate G Proteins
The sequence of transmission
1. Action potential travels down the axon to the axon terminal 2. Voltage-gated calcium channels open and calcium ions (Ca2+) enter. 3. Synaptic vesicles fuse with membrane and release transmitter into the cleft. 4. Transmitters bind to postsynaptic receptors – cause an EPSP or IPSP. …
Phantom Limb Syndrome
Somatosensory Cortex – Representation of the entire body in the mind.
Blind Sight
Occipital lobe is damaged, but superior colliculus is not damaged; see movement but not the object;
Motion Blindness
If superior colliculus is damaged, with occipital lobe not damaged, it would be like seeing a series of pictures
Visual Neglect
Parietal lobe damaged, and spatial interpretation is warped based on the side of the brain damaged (cross-see)
Visual Pathways
How Pathway & What Pathway
How Pathway
Involved in navigation
What Pathway
Recognition and what it means.
Capgras Delusion
Delusions of impostors; Pathway to amygdala severed leading to lack of emotion; that person holds no emotion to the patient therefore must be some kind of impostor.
Temporal Lobe Epilepsy
Overstimulation of emotion; group of neurons fire quickly and sporadically. Intense religious episodes; too many fibers connected to amygdala which causes patient to apply significance to everyday sights. Frontal Lobe; Precentral Gyrus; Central Sulcus; Postcentral Gyrus; Parietal Lobe; O…

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