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Evolution of Vertebrate Lungs The Human Respiratory System
look at lungs
DefenseMechanisms:
Ciliated mucous lining traps inhaled particles in: nose,pharynx, trachea, bronchi
InhalingPolluted Air or Cigarette Smoke
Results in: bronchial constriction, increased mucussecretion, damage to ciliate cells, coughing Can cause: chronic bronchitis, pulmonary emphysema, lungcancer
Effects of Cigarette Smoke: look at diagram
look at diagram
Mechanics of Breathing: look at diagram
look at diagram
RespiratoryMeasurements
Tidal volume: amount of air moved into and out of lungs witheach normal breath Vital capacity maximum volume exhaled after lungs fill tomaximum extent Residual capacity: air volume remaining in lungs at end ofnormal expiration.
Regulationof Breathing
Respiratory center in medulla and pons: regulate respiration Chemoreceptors: sensitive to increased CO2 concentration,stimulate respiratory centers, respond to increase in H+ or very low O2concentration.
GasExchange
O2 and CO2 exchange between alveoli and blood by diffusion
Hemoglobin
· Respiratory pigment in vertebrate blood · Almost 99% of oxygen in human blood istransported as oxyhemoglobin (HbO2)
DivingMammals
Have high concentrations of myoglobin: pigment that storesoxygen in muscles
Effectsof Barometric Pressure
· As altitude increases, barometricpressure falls, less oxygen enters the blood: hypoxia, loss of consciousness,death · Rapid decrease in barometric pressurecan cause decompression sickness: among divers who ascend too rapidly
CO2Transport:
· About 60% of CO2 in blood istransported as bicarbonate ions · About 30% combines with hemoglobin · About 10% is dissolved in plasma
The Human Respiratory System: look at diagram
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Osmoregulation and Disposal of Metabolic Wastes (excretorysystems)
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Fluid-ElectrolyteHomeostasis
· Osmoregulation (water and solutebalance): active regulation of osmotic pressure of body fluids, maintains fluidand electrolyte homeostasis · Excretion: process of ridding body ofmetabolic wastes
NitrogenousWastes
· Ammonia (toxic): excreted mainly byaquatic animals · Urea (less toxic): synthesis requiresenergy, excretion requires water · Uric acid (less toxic): excreted assemisolid paste (conserves water)
Osmoconformers
· Most marine invertebrates · Salt concentration of body fluidsvaries with change in sea water
NephridialOrgans
Help maintain homeostasis: by regulating concentration ofbody fluids, osmoregulation, excretion of metabolic wastes
Protonedphridia, metanephrdia, malphighian tubules à look at diagrams
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TheVertebrate Kidney:
· Excretes nitrogenous wastes · Helps maintain fluid balance byadjusting salt and water content of urine
ClickerQuestion:
If stranded at sea, its not ok to drink oceanwater if your really really thirsty
Adaptationto Habitats
· Fresh water, marine, terrestrialhabitats: different problems for maintaining internal fluid balance, excretionof nitrogenous wastes · Structure and function of vertebratekidney: adapted to various osmotic challenges of different habitats
FreshwaterFishes:
Take in water osmotically: excrete large volume of hypotonicurine
MarineMammals:
Ingest sea water with their food: produce concentratedurine, usable water is a byproduct of metabolism
TerrestrialVertebrates
· Must conserve water: adaptationsinclude efficient kidneys · Endotherms: have a high metabolic rate,produce large volume of nitrogenous wastes
Look at liver and all cells diagram of waste production andexcretion
...· Principal excretory system in mammals · Mammalian kidneys produce urine: passesthrough ureters, to urinary bladder for storage · Urine is released from the body(urination) through the urethra
TheUrinary System
· Principal excretory system in mammals · Mammalian kidneys produce urine: passesthrough ureters, to urinary bladder for storage · Urine is released from the body(urination) through the urethra
KidneyStructure I
· Renal cortex: outer portion of kidney · Renal medulla: inner portion of kidney,contains 8-10 renal pyramids · Renal pyramids: tip of each pyramid isa renal papilla
Kidney Structure 2:
· Urine flows into collecting ducts:which empty through a renal papilla into the renal pelvis (funnel-shapedchamber) · Nephrons: functional units of kidney,each kidney has more than 2 million
NephronStructure
· Each nephron consists of: a cluster ofcapillaries (glomerulus), surrounded by a Bowmman’s capsule, that opens into along, coiled renal tubule · Renal tubule consists of: proximalconvoluted tubule, loop of Henle, distal convoluted tubule
BloodVessels 1
· Blood flows through: o Fromsmall branches of renal artery o Toafferent arterioles o Toglomerular capillaries o Intoan efferent arteriole
BloodVessels 2
Efferent arteriole: delivers blood into peritubularcapillaries that surround the renal tubule Blood leaves kidney through renal vein
ClickerQuestion:
Blood entering a kidney via a renal artery willbe: high in oxygen, low in carbon dioxide, relatively high in excess salts,relatively high in nitrogenous wastes
Clicker Question:
Blood leaving a kidney via a renal vein will be: low inoxygen, high in carbon dioxide, relatively low in excess salts, relatively lowin nitrogenous wastes
UrineProduction
· Filtration: of plasma · Reabsorption: of needed materials · Secretion: of potassium, hydrogen ionsinto renal tubule
Filtration1
· Plasma filters through glomerularcapillaries into Bowman’s capsule · Filtration membrane: permeable walls ofcapillaries, filtration slits between podocytes · Podocytes: specialized epithelialcells, makes up inner wall of Bowman’s capsule
Filtration2:
Filtration is nonselective: small molecules become part offiltrate, glucose, other needed materials metabolic wastes
Reabsorption1:
· About 99% of filtrate is reabsorbedfrom renal tubules into blood · Highly selective process: returnsusable materials to blood, leaves wastes, excess substances to be excreted inthe urine
Secretion
Hydrogen ion, certain other ions, and some drugs areactively transported into renal tubule to become part of urine.
Look at diagram: urine production
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Urine
A watery solution of nitrogenous wastes, excess salts, andother substances not needed by the body
AntidiureticHormone (ADH)
· Posterior pituitary increases ADHrelease: · When body needs to conserve water,responds to increase in osmotic concentration of blood (causes by dehydration). · ADH increases permeability ofcollecting ducts of water: more water is reabsorbed, small volume of urine isproduc…
Endocrine Regulation Endocrine system:
· Endocrine glands, cells, tissues thatsecrete hormones (chemical signals): regulage physiological processes · Signals a wide range of target celltypes · Most endocrine responses are slow: butlong-lasting
NervousSystem
· Helps regulate many endocrine responses · Neurons signal other neurons, musclecells, gland cells: including endocrine cells Responds rapidly to stimuli: transmits electrical and chemical signals
KeyConcepts:
The endocrine and nervous systems work closely together toregulate life processes and maintain homeostasis
KeyConcepts:
Most endocrine processes are regulated by negative feedbacksystems, often involving concentrations of specific ions or chemical compounds
Look at diagram for human endocrine glands LOOK AT TABLE 48_1 FOR SOME ENDOCRINE GLANDS AND THEIRHORMONE FUNCTIONS.
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