BIOL 112 1nd Edition Lecture 15 Outline of Last Lecture I Percent conservation aka percent identity II Genomes tell evolutionary history III Origin nucleus golgi ER IV Paralogs orthologs V Transcription factors DNA binding protiens bind specific sequence in gene promoters control region help recruit RNA polymerase to gene for transcription Outline of Current Lecture VI Hox genes VII Earth is approximately 4 6 billion years old Current Lecture Hox genes o Very important for animal evolution o Hox genes regulate development master regulators control expression of many target genes o Therefore change in hox gene sequence can dramatically impact animal form o Ex Fly hox genes In a specific region control development of all structure in that region o Hox genes are organized in clusters of a gene Gene rated by gene duplication paralogs o Also see Fig 25 23 Earth is approximately 4 6 billion years old o No life before 3 billion years ago o Planet bombarded with ice rock from out of space o Earth hypothesis Haldene and Oparin How building formed initially o 1950s Miller and Urey tested experimentally in lab Amino acids bases not nucleotides Almost right o 2008 based on atmospheric conditions around thermal vents cracks in the ocean Amino acids etc more abundant Close to actual conditions in early Earth These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute
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