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CHEM 2211 -
Synthesis and Retrosynthesis
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CHEM 2211 1st Edition Lecture 23Outline of Last LectureI. Revision and Expansion of Acid-Catalyzed Water AdditionII. Hydroboration of AlkynesOutline of Current LectureI. Know your mechanismsII. Intro to RetrosynthesisIII. Example #1IV. Example #2V. Practice ProblemCurrent LectureI. KNOW YOUR MECHANISMS!!!II. Introduction to RetrosynthesisA. Retrosynthesis is just a synthesis reaction backwardsB. Useful skill for when you have a product but need to create a reactant via the least amount of steps possibleExample #1Retrosynthesis of 3-hexyneSynthesis reaction of ethyne into 3-hexyneExample #2Retrosynthesis of 3, 4-dibromohexaneSynthesis of 3, 4-dibromohexane from ethynePractice ProblemSynthesize this three carbon aldehyde from
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