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UNC-Chapel Hill BIOL 252 - Muscular System I

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Guided reading questions (GRQ) - 10Muscular System ILearning Objectives:59. Compare the structure and function of skeletal muscle, cardiac muscle, and smooth muscle tissue60. Describe the structure and organization of skeletal muscle tissue and how it correlates to movement.61. Describe the structural features of a skeletal muscle fiber62. Describe the sliding-filament theory (mechanism) of muscle contraction63. Compare and contrast the events that take place during skeletal muscle contraction and relaxation64. Predict the roles of Ca2+ and ATP at mediating muscle contraction and relaxationRead Modules 4.4, 9.1, 10.1, 10.2, 10.4Do not hesitate to use the web when a question is not specifically addressed in the textbook----------------------------------------------------------------------------------------------------------Q1. Compare and contrast striated and smooth muscle cells by filling out the table below:CHARACTERISTIC STRIATED SMOOTHPresence of myofibrils?Single ormultinucleated?Presence of gapjunctions?Surrounded byendomysium?Voluntary or involuntarycontrol?Q2. Define the following features of skeletal muscle tissue in 1-2 sentences and in your own words.Muscle fiberEndomysiumFasiclePerimysiumEpimysiumFasciaTendonSkip the following sub-sections in Module 9.1:- Fascicle patterns and muscle shapes- Naming Muscles- Studying MusclesQ3. Define the following terms related to the function of skeletal muscle in 1-2 sentencesand in your own words.ActionAgonistAntagonistSynergistFixatorOriginInsertionQ4. Describe the structure of the following lever systems. This should include the location of four components of a lever: lever, load, force, and fulcrum:Type 1 LeverType 2 LeverType 3 LeverQ5. Describe the five properties of a muscle cell in your own words (and in 1-2 sentences)1.2.3.4.5.Q6. Describe the following structural features of a muscle cell in 1-2 sentences and in your own words.SarcoplasmSarcolemmaMyofibrilsSarcoplasmic reticulum (SR)Transverse tubules (T-tubules)Terminal cisternae TriadMyofilamentsThick filamentsThin filamentsElastic filamentsSarcomereQ7. Differentiate between the three types of thin filaments by describing in 1 sentence and in your own words the difference between the following:ActinTropomyosinTroponinQ8. Describe the organization of a sarcomere by identifying the following features in 1-2sentences and in your own words (hint - refer to Study Boost in Module 10.2):A bandH zoneM lineI bandZ discQ9. Compare and contrast how the following components of a sarcomere change in a relaxed vs. contracted muscle fiber.STRUCTURAL FEATURE RELAXED CONTRACTEDI bandH bandA bandZ discM lineQ10. True/False (Explain): Muscle cells are capable of propagating an action potential Q11. What is the resting membrane potential of a muscle cell?Q12. True/False (Explain): Motor neurons stimulate skeletal muscle cells via acetylcholine.Q13. True/False (Explain): An action potential that is propagated in a skeletal muscle cell opens calcium channels located in the sarcolemma.Q14. True/False (Explain): Elevated cytosolic calcium is associated with skeletal muscle contraction while reduced cytosolic calcium is associated with skeletal muscle relaxation.Q15. True/False (Explain): ATP is hydrolyzed by troponin to expose the active site of actin, allowing myosin to bind during muscle


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