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UNC-Chapel Hill BIOL 252 - Synaptic activity

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Guided reading questions (GRQ)-5Synaptic activityLearning Objectives:26.Contrast between electrical and chemical synapses27.Describe the events that occur at a chemical synapses28.Differentiate between ionotropic and metabotropic neurotransmitter receptors29.Predict the outcomes of excitatory postsynaptic potentials and inhibitory postsynaptic potentials30.Compare temporal and spatial summation of postsynaptic potentials31.Describe the three mechanisms by which synaptic transmission is terminated32. Identify and compare the major neurotransmittersRead Modules 11.4 and 11.5. Do not hesitate to use the web when a question is not specifically addressed in the textbook.---------------------------------------------------------------------------------------------------------------Q1. In your own words, define the following terms:Presynaptic neuronPostsynaptic neuronSynaptic cleftExcitatory postsynaptic potential (EPSP)Inhibitory postsynaptic potential (IPSP)SummationTemporal summationSpatial summationIonotropic receptorMetabotropic receptorSecond messengerG-proteinQ2. What facilitates the transport of information from the presynaptic neuron to the postsynaptic neuron in a chemical synapse?Q3. What facilitates the transport of information from the presynaptic neuron to the postsynaptic neuron in an electrical synapse?Q4. What stimulates the Ca2+ gated channels to open in the synaptic knob?A. Ca2+ binding to its receptorB. Voltage changes in the axolemmaC. Primary active transport that pumps Ca2+ From the cytosol to the extracellular fluid.Q5. In 1-2 sentences each, describe the three mechanisms by which synaptic transmission is terminated:1.2.3.Q6. What will happen if the neurotransmitter, after being released from the synaptic vesicles, will not be absorbed or


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