Guided reading questions GRQ 5 Synaptic activity Learning Objectives 26 Contrast between electrical and chemical synapses 27 Describe the events that occur at a chemical synapses 28 Differentiate between ionotropic and metabotropic neurotransmitter receptors 29 Predict the outcomes of excitatory postsynaptic potentials and inhibitory postsynaptic potentials 30 Compare temporal and spatial summation of postsynaptic potentials 31 Describe the three mechanisms by which synaptic transmission is terminated 32 Identify and compare the major neurotransmitters Read Modules 11 4 and 11 5 Do not hesitate to use the web when a question is not specifically addressed in the textbook Q1 In your own words define the following terms Presynaptic neuron Postsynaptic neuron Synaptic cleft Excitatory postsynaptic potential EPSP Inhibitory postsynaptic potential IPSP Summation Temporal summation Spatial summation Ionotropic receptor Metabotropic receptor Second messenger G protein Q2 What facilitates the transport of information from the presynaptic neuron to the postsynaptic neuron in a chemical synapse Q3 What facilitates the transport of information from the presynaptic neuron to the postsynaptic neuron in an electrical synapse Q4 What stimulates the Ca2 gated channels to open in the synaptic knob A Ca2 binding to its receptor B Voltage changes in the axolemma C Primary active transport that pumps Ca2 From the cytosol to the extracellular fluid Q5 In 1 2 sentences each describe the three mechanisms by which synaptic transmission is terminated 1 2 3 Q6 What will happen if the neurotransmitter after being released from the synaptic vesicles will not be absorbed or destroyed
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