GENE 412 1st Edition Lecture 10 Outline of Last Lecture I Assortative Mating Selection II Examples Outline of Current Lecture I Disassortative Mating Selection II Examples III Adding Mixtures of two species into one population Current Lecture I II Disassortative Mating Selection a Definition Unlike individuals for a specific locus mating b Characteristics i More Heterozygotes ii Powerful one locus evolutionary force iii Maintains Diversity iv Allelic Frequency Changes c Reason for above characteristics i Double heterozygotes breaks down Hardy Weinburg Equlibrium ii Involves many alleles d Equation for determining frequency of heterozygotes in a population i At equilibrium all Aa F a F A 0 5 ii For n alleles F An 1 n Examples of Disassortative Mating a HLA Locus i Very prominent in humans 1 Shows most married couples chose opposite genotype for HLA Locus than their spouse ii Can change allelic frequency dramatically in one population iii P a 25 1 AA X Aa Aa X aa AA X aa are the only possible parental mating patterns for Disassortative mating 2 After one generation of only these mating studies showed P a 375 These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute III Mixing of two species in one population a European and African Honey Bee Mating i European Honey Bee f A 8 f B 6 ii African Honey Bee f A 2 f B 4 b Migration effect in population i Mixture of population coming together ii mAf 8 iii meuro 2 c Another equation used for determining D i D m 1 m p1 p2 k1 k2 ii D can be positive or negative iii D is the measure of recombination or mixing of the genome iv So for the information above about the African European Honey Bee 1 D 8 2 8 2 6 4 0192