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UT Knoxville BCMB 230 - 10:8:13

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Skeletal MuscleMotor implatewhen i release acetyl choline im gonna enough nicotinic receptors and get an action potentialdoes down to t-tubule then goes down through the t-tubule. The ­­­­­­_dhp____ protein goes for a riodine recepotor which later opens the calciumdhp receptor responds to the voltage change by changing its shape. Actually a calcium receptor then calcium goes down into the cystocsol then bind to troponin pull tropmyosin out of the way then start a cross-bridge cycle… which is a repetitive cycle of thisso four steps for cross bridge cycle:1. Make the Cross bridge. Calcium coming in move tropomysoin away- make a bond with actin and myosin2. Cross bridge moves3. break the cross bridge (break the bond)4. change the shape of myosin head (energize the myosin)the cycle doesn’t provide movement but it provides tension. But can provide movement with how much tension produced.Myosisn still has hydrolysis products. Adp and p?Calcium role:Atp roles:break^^^^ memorizeLatent period:All or none: rule we kinda followTreppe- get an increase in amount of tension with each muscle twitch (/contraction) the environmental conditions are changing around it might have been temperature, ion availability, the way the muscles work when its cold or operating temperature as the muscles move they heat up a little so it works better when the muscle is being used.Unfused tetanus - get a little more contraction before its fully relaxed. This is faster. These are frequency tension relationshipsFused tetanus- is when you stimulate at the peak so it never relaxes. Is a good thing because I can control it can turn it on and off- theseTrepp and tetanus break the all or none rule by changing the conditions/ frequency of the stimulouswhen I stretch a sarcomere the amount of actin and myosin overlap isthe number of cross bridges affects the strength of the tension production.length tension relationship- we have an optimal length. The more stretched a muscle is the lower the tension in a muscle contraction. If I compress it the contraction strength decreases. Because this is skeletal muscle its attached to bone… so its already at its optimal length cant really change it. But some muscles can stretch outside of this like muscles in teeth?Muscle contraction requires energy…..have to have ATP to drive cross-bridge cycleCreatine phosphateif I want a sustainable with fewest amount of bi products we go through oxidative phosphorlation. Kreb cycle. We need glucose. Then we have CO2 which is relatively easy for us to get rid of.- 10/8/13 10/08/2013Skeletal Muscle-Motor implate-when i release acetyl choline im gonna enough nicotinic receptors and get an action potential -does down to t-tubule then goes down through the t-tubule. The -_dhp____ protein goes for a riodine recepotor which later opens the calcium -dhp receptor responds to the voltage change by changing its shape. Actually a calcium receptor then calcium goes down into the cystocsol then bind to troponin pull tropmyosin out of the way then start a cross-bridge cycle… which is a repetitive cycle of this-so four steps for cross bridge cycle:o1. Make the Cross bridge. Calcium coming in move tropomysoin away- make a bond with actin and myosino2. Cross bridge moveso3. break the cross bridge (break the bond)o4. change the shape of myosin head (energize the myosin)-the cycle doesn’t provide movement but it provides tension. But can provide movement with how much tension produced. -Myosisn still has hydrolysis products. Adp and p? -Calcium role:-Atp roles:obreak o^^^^ memorize -Latent period: -All or none: rule we kinda follow-Treppe- get an increase in amount of tension with each muscle twitch (/contraction) the environmental conditions are changing around it might have been temperature, ion availability, the way the muscles work when its cold or operating temperature as the muscles move they heat up a little so it works better when the muscle is being used.-Unfused tetanus - get a little more contraction before its fully relaxed. This is faster. These are frequency tension relationships-Fused tetanus- is when you stimulate at the peak so it never relaxes. Is a good thing because I can control it can turn it on and off- these-Trepp and tetanus break the all or none rule by changing the conditions/ frequency of the stimulous-when I stretch a sarcomere the amount of actin and myosin overlap is -the number of cross bridges affects the strength of the tension production.-length tension relationship- we have an optimal length. The more stretched a muscle is the lower the tension in a muscle contraction. If I compress it the contraction strength decreases. Because this is skeletal muscle its attached to bone… so its already at its optimal length cant really change it. But some muscles can stretch outside of this like musclesin teeth? Muscle contraction requires energy…..-have to have ATP to drive cross-bridge cycle-Creatine phosphate-if I want a sustainable with fewest amount of bi products we go through oxidative phosphorlation. Kreb cycle. We need glucose. Then we have CO2 which is relatively easy for us to get rid of.


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UT Knoxville BCMB 230 - 10:8:13

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