Chem150 - Survey of BiochemistryIntroductionOrganic ChemistrySlide 4Slide 5Slide 6Slide 7Slide 8Slide 9Slide 10Slide 11Slide 12Slide 13Survey Question (Clicker)Slide 15Nalgene polycarbonatesORGANIC MOLECULE IN THE NEWS: Bisphenol APHARMACOPHORE IN THE NEWS: Bisphenol ABiochemistrySlide 20Slide 21Slide 22Slide 23Chem150 - Survey of BiochemistryIntroductionChem150, University of Wisconsin-Eau Claire Introduction 2Introduction•The chemistry we will focus on this semester•Organic Chemistry•The chemistry of carbon•Functional groups•Biochemistry•The chemistry of living systemsChem150, University of Wisconsin-Eau Claire Introduction 3Organic ChemistryChem150, University of Wisconsin-Eau Claire Introduction 4Organic Chemistry•Hydrocarbons represent the starting point•Contain only carbon and hydrogen•Groups include Alkanes, alkenes and alkynesC C C CH H H HHHHHHHButaneChem150, University of Wisconsin-Eau Claire Introduction 5Organic Chemistry•Organic molecule are organized into functional groups•Many contain elements other than carbon and hydrogen•Oxygen•Nitrogen•Sulfur•Halogens (F, Cl, Br, & I)Chem150, University of Wisconsin-Eau Claire Introduction 6Organic ChemistryChem150, University of Wisconsin-Eau Claire Introduction 7Organic Chemistry•Functional Groups•Hydroxyl groups (alcohols)C C C CH H H HOHHHHH HHydroxylGroup1-ButanolChem150, University of Wisconsin-Eau Claire Introduction 8Organic Chemistry•Functional Groups•Amino groups (amines)C C C CH H H HNHHHHH HH1-ButylamineAminoGroupChem150, University of Wisconsin-Eau Claire Introduction 9Organic Chemistry•Functional Groups•Carbonyl groups (aldehydes and ketones)C C C COHHHHHHHHButanalAldehydeGroupChem150, University of Wisconsin-Eau Claire Introduction 10Organic Chemistry•Functional Groups•Carboxyl groups (carboxylic acids)C C C COO HHHHHHHHButanoic acidCarboxylGroupChem150, University of Wisconsin-Eau Claire Introduction 11Organic Chemistry•Functional Groups•Functional group affect the physical and chemical properties of organic molecules.Butane (alkane) Butanol (alcohol) Butylamine (amine)Butanoic acid (carboxylic acid)Butanal (aldehyde)waterChem150, University of Wisconsin-Eau Claire Introduction 12Organic Chemistry•Functional Groups• chemical structure affects drug or hormone-receptor interactionsChem150, University of Wisconsin-Eau Claire Introduction 13Organic Chemistry•Functional Groups• Is this even possible? Or this?http://www.ftc.gov/opa/2008/08/airborne.shtmhttp://www.ftc.gov/opa/2007/08/hoodia.shtmChem150, University of Wisconsin-Eau Claire Introduction 14Survey Question (Clicker)•Do you think there is some validity to HeadOn as a headache cure?A) YesB) NoC) I don’t knowWhat chemical questions would you want to have answered to decide ?Chem150, University of Wisconsin-Eau Claire Introduction 15Survey Question (Clicker)Do you have concerns about Nalgene bottles and health risks (esp to babies)?A) YesB) NoC) I don’t knowWhat chemical questions would you want to have answered to decide ?Chem150, University of Wisconsin-Eau Claire Introduction 16Nalgene polycarbonatesWhat chemical questions would you want to have answered to decide ?Chem150, University of Wisconsin-Eau Claire Introduction 17ORGANIC MOLECULE IN THE NEWS: Bisphenol AQuickTime™ and aTIFF (LZW) decompressorare needed to see this picture.QuickTime™ and aTIFF (Uncompressed) decompressorare needed to see this picture.Chem150, University of Wisconsin-Eau Claire Introduction 18PHARMACOPHORE IN THE NEWS: Bisphenol Ahttp://e.hormone.tulane.edu/learning/estrogens.htmlChem150, University of Wisconsin-Eau Claire Introduction 19Biochemistry•Biological molecules•Amino acids and Proteins•Carbohydrates and Polysaccharides•Nucleotides and Nucleic acids•Lipids (Fats, oils)Chem150, University of Wisconsin-Eau Claire Introduction 20Biochemistry•Biological molecules•Amino acids and ProteinsCNHCOO HCHHHHHAminoGroupCarboxylic AcidGroupAlanineChem150, University of Wisconsin-Eau Claire Introduction 21Biochemistry•Biological molecules•Carbohydrates and PolysaccharidesHOOHHHOHOHOHHHOHGlucoseChem150, University of Wisconsin-Eau Claire Introduction 22Biochemistry•Biological molecules•Lipids (Fats, oils)H3CH2CCH2H2CCH2H2CCH2H2CCH2H2CCH2H2CCH2H2CCH2H2CCOO CH2CHCH2H3CH2CCH2H2CCH2H2CCH2H2CCH2H2CCH2H2CCH2H2CCH2H2CCOOH3CH2CCH2H2CCH2H2CCH2H2CCH2H2CCH2H2CCH2H2CCH2H2CCOOTriglycerideChem150, University of Wisconsin-Eau Claire Introduction 23Biochemistry•Biological Macromolecules•Proteins, Polysaccharides and Nucleic Acids•Metabolism•Taking things apart•Putting things together•Obtaining and using energy•Regulation of