VOL.48,1962PSYCHOLOGY:GAZZANIGA,BOGEN,ANDSPERRY1765Someofthesestudieshavebeenreportedinapreliminarycommunication,Hoffee,P.,andE.Englesberg,Bacteriol.Proc.,1962,p.120.Abbreviations:ATP,adenosinetriphosphate;aMG,alphamethylD-glucopyranoside.tPredoctoralResearchFellow,U.S.PublicHealthService.lRickenberg,H.V.,G.N.Cohen,G.Buttin,andJ.Monod,Ann.Inst.Pasteur,91,829(1956).2Cohen,G.N.,andJ.Monod,Baderiol.Revs.,21,169(1957).3Kepes,A.,Biochim.Biophys.Acta,40,70(1960).4Horecker,B.L.,J.Thomas,andJ.Monod,J.Biol.Chem.,235,1580(1960).5Horecker,B.L.,J.Thomas,andJ.Monod,J.Biol.Chem.,235,1586(1960).6Osborn,M.J.,W.L.McLellan,Jr.,andB.L.Horecker,J.Biol.Chem.,236,2585(1961).7Rotman,B.,andR.Guzman,Pathologie-Biologie,9,806(1961).8Wiesmeyer,H.,andM.Cohn,Biochim.Biophys.Acta,39,440(1960).9Doudoroff,M.,W.Z.Hassid,andE.W.Putman,J.Biol.Chem.,179,921(1949).'0Englesberg,E.,J.A.Watson,andP.A.Hoffee,inCellularRegulatoryMechanisms,ColdSpringHarborSymposiaonQuantitativeBiology,vol.26,(1961)p.261.11Englesberg,E.,thesePROCEEDINGS,45,1494(1959).12Umbreit,W.W.,R.H.Burris,andJ.F.Stauffer,ManometricTechniques (Minneapolis:BurgessPublishingCompany,1957).13Dische,Z.,andE.Borenfreund,J.Biol.Chem.,192,533(1951).14Barett,J.T.,A.D.Larson,andR.E.Kallio,J.Bacteriol.,65,187(1953).15Davis,B.D.,inEnzymes:UnitsofBiologicalStructureandFunction,ed.0.H.Gaebler(NewYork:AcademicPress,1956),p.509.SOMEFUNCTIONALEFFECTSOFSECTIONINGTHECEREBRALCOMMISSURESINMAN*BYM.S.GAZZANIGAfJ.E.BOGEN,l:ANDR.W.SPERRYtCALIFORNIAINSTITUTEOFTECHNOLOGY,*PASADENA,ANDLOMALINDAUNIVERSITYSCHOOLOFMEDICINE,LOSANGELESCommunicatedAugust2,1962Ithasbeenpossibleinstudiesofcallosum-sectionedcatsandmonkeysinrecentyearstoobtainconsistentdemonstrationofavarietyofinterhemisphericintegra-tionalfunctionsmediatedbythecorpuscallosum.1'2Theseanimalfindingsstandinmarkedcontrasttotheapparentlackofcorrespondingfunctionaldeficitspro-ducedbysimilarsurgeryinhumanpatients.3-9Thegeneralpictureofcallosalfunctionsbasedontheanimalstudiestendstobesupportedincurrentearlytestingofa48-year-oldmalewarveteranwithrecentcompletesectionofthecorpuscal-losum,anteriorandhippocampalcommissures.Thepatient(W.J.)hadbeenhavinggrandmalconvulsionsforfifteenyearssub-sequenttowarinjuriessufferedin1944.Theseizureswererefractorytomedicalmanagementwithafrequency,atbest,ofabout1perweekand,at
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