UW-Madison BME 400 - What is FNA (19 pages)

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What is FNA



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What is FNA

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Pages:
19
School:
University of Wisconsin, Madison
Course:
Bme 400 - Capstone Design Course in Biomedical Engineering
Capstone Design Course in Biomedical Engineering Documents

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Problem Statement GOAL To modify the needle used during a Fine Needle Aspiration FNA procedure The modification should not drastically change the FNA procedure and still increase the amount of tissue removed for cytological testing It should also minimize the time by collecting an adequate sample size on the first attempt and discomfort caused to the patient during the procedure What is FNA Technique used to extract cells no incision needed Several insertions are usually required to ensure an adequate sample size Samples are sent to pathologist to be analyzed National Breast Cancer Center http www NBCC org Fine Needle Aspiration FNA A D A M http www adam com Product Design Specifications Removes adequate number of cells for diagnosis Should not cause more discomfort than current FNA procedure Constrained to standard 20 25 gauge needle client prefers 23 gauge Current Prototype Pre manufactured drill bit 6 length Fits in 23 gauge needle Tissues Tested Fixed cat tissues Mammary Lymph Fat Testing Procedures Old technique No insert used Performed two separate trials on all three tissues New technique Drill bit insert used Performed two separate trials on all three tissues Observed in saline bath under microscope Sample Quantification Old technique Resulted in either a mass of cells or a minimal quantity of cells New technique More dispersed cell sample Greater number of cells on average Future Work Further prototype development Research into appropriate materials to be used stainless steel Co Cr Ti Develop protocol for quantifying testing Test on freshly removed tissue In vivo testing of animal tumors Cytological evaluation Drill Bit Size Comparison Tissue Sample Mammary Tissue Sample Lymph Tissue Sample Fat Old Technique Mammary Old Technique Lymph Old Technique Fat New Technique Mammary New Technique Lymph New Technique Fat



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