MCDB 100 Introduction to Cell Biology Syllabus Fall Quarter 2008 Sept 25, 2008 Instructor: Paul O’Lague ([email protected]) Lect: Tu Thr 12:30 – 1:45 pm KNSY PV 1220B Office Hours: TBA LS 4209 Note: No discussions first week Class Text: Molecular Biology of the Cell. Alberts et al. 5th Edition (earlier OK) Class Web Site: http://www.lsic.ucla.edu/classes/fall08 Lect Date Lecture Topics Chapt Reading 1 Sept 25 Origins, why cells General design Principles 1:review optional reading 2 30 Review: Chemical and Energetic Foundations 2: p. 45-54; p. 65 – 80; panels 2-1,2-2,2-3,2-7 3 Oct 2 Methods, cells, and viruses 9: to p.603 4 7 Cell Membrane 10, panel 2-5 5 9 Diffusion Processes 11: p.651-667 6 14 Active Transport 11: p.651-667 7 16 Bioenergetics I 2: p.80-100; panel 2-8, 2-9 8 21 Bioenergetics II 2: p.80-100; panel 2-8, 2-9 9 23 Signals: receptors, second messengers 15: to p. 942 10 28 Signals: G-Proteins, kinases, gene regulation 15: to p. 942 30 Midterm 11 Nov 4 Protein Trafficking 12,13:to p.787 12 6 Intercellular Signals I 11: p.667 to end 13 11 Intercellular Signals II 11: p.667 to end 14 13 Cell forces, shape, cytoskeleton 14, 16 15 18 The Nucleus 12: p.704-712 4: p.239-245 16 20 The Cell Cycle 1 17: to p.1067; p. 1071 to end 17 25 The Cell Cycle 2 17: to p.1067; p. 1071 to end 27 Thanksgiving 18 Dec 2 Cancer – oncogenes 20 19 4 Multicellular Design 19 11 Final Exam 11:30am-2:30 pm ;Rooms TBAWeekly Assignments: problem sets/research papers account for 20% of grade Discussion Sections 1A T 2:00P Botany 133 1B T 3:00P Botany 133 1D W 11:00 A Botany 133 1E W 12:00P Botany 133 1F W 1:00P Botany 133 1G R 2:00P Botany 133 TA E-mail Office Hours Room Andrew Goldstein [email protected] TBA TBA Seanna Martin [email protected] TBA