MCDB 100 Introduction to Cell Biology Syllabus Winter Quarter 2008 Jan 8, 2008 Instructor: Paul O’Lague ([email protected]) Lect: Tu Thr 12:30 – 1:45 pm MS 4000 Office Hours: TBA LS 4209 Note: No discussions first week Class Text: Molecular Cell Biology. Lodish et al. 6th Edition (earlier OK) Class Web Site: http://www.lsic.ucla.edu/classes/winter07 Lect Date Lecture Topics Chapt Reading 1 Jan 8 Origins, why cells? General design Principles 1 2 10 Review: Chemical and Energetic Foundations 2, 3.3 3 15 Methods, cells, and viruses 5.5,5.6,6.7 Class Notes 4 17 Cell Membrane 5 5 22 Diffusion Processes 7.1,7.4,7.5, 6 24 Active Transport 7.2 7 29 Bioenergetics I 8.1- 8.3 8 31 Bioenergetics II 8.1- 8.3 9 Feb 5 Signals: receptors, second messengers 13 10 7 Signals: G-Proteins, kinases, gene regulation 14 12 Midterm (27% of grade) in class 11 14 Protein Trafficking 16 12 19 Intercellular Signals I 7.3,7.7 13 21 Intercellular Signals II 7.8 14 26 Cell forces, shape, cytoskeleton 3.4,5.4,19,20 15 28 The Nucleus 12.3,12.4,21.4 Class Notes 16 Mar 4 The Cell Cycle I 21 18 6 Cancer – oncogenes I 23 19 11 Cancer – oncogenes II 23 20 13 Review 18 Final Exam (53% of grade) 8:00-11:00am; MS 4000 Weekly Assignments: problem sets/research papers account for 20% of gradeDiscussion Sections 1A T 2:00P LS4127 1B T 3:00P LS4127 1C T 4:00P LS4127 1D W 9:00A LS4127 1E W 10:00A LS4127 1F W 11:00A LS4127 TA E-mail Office Hours Room Andrew Goldstein [email protected] TBA TBA Aya Westbrook [email protected] TBA