Damage to the nervous system Damage to the nervous system retrograde degeneration anterograde degeneration Regrowth problems Regrow Peripheral nervous system PNS Central nervous system CNS embryonic distinction Myelin oligodendrocytes vs Schwann cells Nogo Collateral axon sprouting Part of new circuit solution Denervation supersensitivity Loss of synapses Increase in neurotransmitter receptor Parkinson s disease loss of dopamine in axons from substantia nigra to striatum caudate putamen Increased dopamine receptors response to L DOPA Parkinson s disease symptoms tremor trouble initiating movements eventual cognitive decrements
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