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Protein
Long chain of amino acids
Amino = ?
Nitrogen
Peptide Bond -dipeptide -polypeptide
Links together 2 amino acids -2 amino acids chemically joined -more than 2
Protein is an _______ nutrient.
Essential (cannot be made by body)
Essential Amino Acid (3)
-Cannot be made by body (must be in diet) **PROVIDE A SOURCE OF NITROGEN FOR OTHER COMPOUNDS -Can be used as an energy source
Non-essenital Amino Acids (3)
-Body is able to make from other sources -Source of nitrogen for other compounds -Can be used as an energy source
Functions of Proteins (8)
-Structure -Growth -Maintenance and repair of body tissues -Energy -Hormone Production -Blood proteins -Enzymes -Immune Function
Blood Proteins (4)
-Regulation of fluid & acid/base balance -Blood clotting -Delivery of O2 to tissues -Transport proteins
Enzyme Proteins-Speed up and control...(3)
-Digestion -Absorption -Metabolism
**Denaturation
Results in a loss of protein function and exposure of peptide bonds for digestion (fist step of digestion)
Protein Digestion-Mouth
Grinding and mixing of food
Protein Digestion-Stomach (3)
-Protein structure denatured with acid -Acid breaks bonds -Pepsin (enzyme) breaks more bonds
Protein Digestion-Pancreas
Enzymes secreted into small intestine
Protein Digestion-Small Intestine (2)
-Proteins digested by pancreatic enzymes -Small peptides broken into dipeptides
In the adult, all protein must be absorbed as _______ or ________.
Amino acids or Dipeptides
Protein Absorbtion-Small Intestine (4)
-Taken up into the enterocyte -Released as amino acids into capillaries -Capillaries > portal vein -Portal vein > liver
Protein Absorbtion-Liver 
Regulates level of amino acids in blood 
TRANSamination
TRANSfer of an amine group from an amino acid to form a new amino acid **Used for formation of nonessential amino acids, need vitamin B6
Deamination
Removal of the amino group from an amino acid -Used for energy production, B6 needed
Protein Intake (2)
-Better usage when lower -Poorer usage when high (used for energy)
Protein Quality
Animal proteins, moist cooking = more digestible
Complete proteins
Animal sources
Incomplete proteins
Plant sources
Complementary Proteins
Combination of complete & incomplete > high quality protein intake
Need for Protein (6)
-Maintenence -Pregnancy -Lactation -Growth -Exercise -Disease
Protein Requirement
0.8 g/kg body wight
Vege Diets-Pros (3)
-Low in sat fat/chol. -High fiber -High vit./min.
Vege Diets-Cons (5)
-Low iron -Low calcium -Low energy -Low protein density (preg.women & children) -Low in B12 (vegans only)
Protein Deficiency
Kwashiorkor (Protein Malnutriton) -swollen belly (Edema) -impaired growth/immune Marasmus -look starved/wasted away
Protein Supplements (Downfalls-2)
-Not really useful -Can be toxic
Vitamin B6 Funtions (4)
-Amino acid metabolism -DNA metabolism -Immune function -Cognitive function
Anabolism
Basic building units used to build body compounds
Catabolism
Break down the basic building units for energy and excretion
Metabolic Pathways (4)
-Glucose -Amino acids -Fatty acids -Alcohol
Directly or indirectly _______ are involved in energy metabolism
Vitamins
Thiamin B1 (function)
-Coenzyme for energy metabolism -Nerve function
Thiamin B1 (Deficiency)
Beriberi Wet-Edema (swollen belly), heart failure Dry-Weakness, paralysis
Thiamin B1 (sources)
**PORK -whole grains -green leafy veggies
Riboflavin B2 (function)
-Transfer of energy to ATP
Riboflavin B2 (sources)
**MILK -whole grains -green leafy veggies
Niacin (functions-2)
-Transfer of energy to ATP -Formation of fatty acids
Niacin (deficiency)
Pellagra -dimensia -dermatitus -diarrhea -death Alcoholics & low protein intake
Pantothenate-B vitamin (functions-2)
-Aerobic energy metabolism -Fatty acid synthesis
Pantothenate-B vitamin (sources)
-Pan (found everywhere) -Whole grain, meat, milk
Biotin-B vitamin (function)
-Energy metabolism
Biotin-B vitamin (dietary sources)
-Meat -Milk -Egg yolks -Nuts
Chromium (functions-2)
-Helps insulin function for increasing glucose uptake -Needed for energy release from glucose
Chromium (sources)
-Whole grains -Liver -Seafood
**Iodine (functions-2)
-Part of thyroid hormone -Energy metabolism regulation
Iodine (deficiency)
Goiter-hyper enlargement of thyroid gland
Iodine (sources)
-Iodized salt -Seafood -Baked goods
Iodine (special notes)
TOXIC in large quantities>goiter
Hunger
Physiological drive to eat
Appetite
Psychological drive to eat
Satiety
Hunger & appetite satisfied
Intake>Expenditure
Catabolic
Body Fat Equivalence
I lb. = 3,500 calories
Components of Energy Expenditure (4)
Metabolism: 60-70% Physical Activity: 13-35% Thermic Effect of Food: 5-10% Heat Production
Basal Metabolic Rate (BMR)
Resting energy expenditure as soon as you wake up
Increase BMR (6)
-Lean body mass -Height up -Fever -Pregnancy -Env. Temp up -Thyroxin up
Decrease BMR (5)
-Increasing age -Starvation -Height down -Env. temp down -Thyroxin down
Health Risks w/ Obesity (7)
-Cardiovascular disease -Hypertension -Non-insulin dependent diabetes -Cancer -Osteoarthritus -Increased risks during surgery -Emotional disturbances
Indirect diagnosis of Obesity (4)
-Body weight -BMI (weight/height*703) -Body fat distribution-android=apple, gynecoid=pear -Percent body fat
Theories of Obesity (4)
-Energy Imbalance (carbs/fat) -Genetics -Metabolism -Environment
Weight Loss program (long term)
-Moderation -Exercise -Balance foods -Breakfast -Self Monitoring
Weight Loss Program (poor)
-Low energy diet -Restrict carbs -Formulas/special products -No activity -No maintence
Weight Loss Medications (2)
-Sibutramone (Meridia)-removed -Orlistat (Xenical)
Bariatric Surgery (Bypass) Pros (2)
-Significant weight loss in short time -Other health improvements
Bariatric Surgery (Bypass) Cons (6)
-Surgical risks -Nutrient deficienies (B12) -Cost -Follow up surgery -Stomach adapts back -People eat more, less often
Weight Cycling
Yo-yo dieting (gain more weight than lost after diet)
Successful Weight Loss (3)
-Control calories -Correct problem behavior -Regular physical activity
Cancer
Cells multiply out of control and disrupt normal functioning
NEoplasm
NEw growth Benign or malignant
Tumor
Rapid and/or uncontrolled increase in number of cells *Mass of neoplasms
Carcinogen
Cancer causing substance Ex. sunlight, x-rays, pesticides
Cancer promoters (3)
-Alcohol -High estrogen -Dietary fat
Dietary cancer reducers (5)
-High fiber -Fruits & veggies >>antioxidants >>phytochemicals -Low fat -Moderate alcohol -Calorie reduction
Oxidation (2)
-Change in structure of a molecule -Caused by free radicals
Antioxidants
React with free radicals to make them less harmful Ex. Vitamin A (carotenoids), C, E, Selenium, copper, zinc
Vitamin C (functions-3)
-Immune -Protects lungs -Increase iron absorption
Vitamin C (deficiency)
Scurvy-teeth and gum problems
Vitamin C (sources)
-Citrus -Tomato -Dark green veggies
Vitamin E (function)
Antioxidant for lipids in the body
Vitamin E (deficiency)
Anemia
Vitamin E (sources)
-Plant oils -Whole grains -Nuts & seeds
Vitamin A & Beta Carotene (functions-3)
-Vision -Cell differentiation -Bone health
Vitamin A (sources-2)
-Fortified milk -Eggs
Carotenoids (sources-3)
-dark green veggies -dark orange fruit
Selenium (function)
Cofactor for an antioxidant enzyme
Selenium (source)
-Whole grain
Phytochemicals & Zoochemicals (functions-2)
-Give color, flavor, odor, protection to plants -Antioxidant properties
Phytochemical & Zoochemical (sources-3)
-Carotenoids -Spices -Tea
Antioxidants protect against...(4)
-Heart disease -Age related disease -Diabetes -Cancer
Bone & Skeleton (functions-5)
**Storage of calcium and phosphate -Support -Protection -movement -Formation of blood cless
Bone composition
99% of all the calcium in the body 
Calcium (functions-5)
-Bone structure -Nerve transmission -Muscle contraction -Blood Clotting -Vascular control
Phosphorus (functions-2)
-part of DNA & RNA -component of bone
Flouride (function)
-Makes teeth resisitant to dnetal caries
Flouride (sources)
-Public drinking water -toothpaste -seafood
Vitamin D (functions-3)
-Bone metabolism -Calcium absoption by intestine -Calcium reabsorption by kidney
Vitamin D (defiency)
-Kids: Rickets -Adults :Osteomalacia
Vitamin C is Needed to make
Collagen
Osteoporosis
Loss of bone mineral and protein (matrix)

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