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Produces streptolysins, toxins, streptokinase, hyaluronidase, deoxyribonucleases, and proteases
Streptococcus pyogenes
Its M protein in cell wall interferes with complement
Streptococcus pyogenes
causes strep throat
Streptococcus pyogenes
causes tonsillitis and ear infections
Streptococcus pyogenes
causes impetigo (pyoderma; red sores that rupture quickly to form yellowish brown crust) and erysipelas (painful, red, swollen rash on cheeks and bridge of nose)
Streptococcus pyogenes
causes Toxic Shock Syndrome
Streptococcus pyogenes
causes Scarlet Fever - bacteria infected with a phage produce erythrogenic toxin (inflammation, reddening of the skin)
Streptococcus pyogenes
causes necrotizing fasciitis (flesh eating)
Streptococcus pyogenes
Due to a phage infection, produces an exotoxin
Corynebacterium diphtheria
Until 1935, #1 cause of death in children in U.S.
Corynebacterium diphtheria
Toxin damages major organs and destroys white blood cells
Corynebacterium diphtheria
Pseudomembrane forms in throat - suffocation
Corynebacterium diphtheria
Early treatment with antitoxin can't neutralize toxin already bound to tissue
Corynebacterium diphtheria
Causes diphteria, conjunctivitis, bull neck, severe myocarditis
Corynebacterium diphtheria
Begins as respiratory tract infection; moves to blood/brain and kills quickly
Neisseria meningiditis
Lipid A causes shock - inflammation, fever, vasodilation, DIC, and petechiae (small skin hemorrhages)
Neisseria meningiditis
Vaccine available for military installations, prisons, classrooms; college students living in dorms
Neisseria meningiditis
Type b was #1 cause of children's meningitis before vaccine developed
Haemophilus influenzae
Hib vaccine developed to treat desease
Haemophilus influenzae
Causes ear infections, pink eye, epiglottitis, and pneumonia
Haemophilus influenzae
Does NOT cause influenza
Haemophilus influenzae
Causes whopping cough and is extremely contagious
Bordetella pertussis
Attaches to ciliated epithelial cells with a capsule and destroys these cells with a toxin
Bordetella pertussis
Can't move mucous b/c of 1st toxin; second toxin gets into blood stream and causes sytemic symptoms
Bordetella pertussis
Infant mortality - can't cope; brain damage; broken ribs
Bordetella pertussis
Chronix couch in adults that lasts for months
Bordetella pertussis
DTaP & Tdap vaccines
Bordetella pertussis
Waterborne organism
Pseudomonas aeruginosa
Causes urinary tract, lung, and wound infections
Pseudomonas aeruginosa
Causes dermititus and "swimmer's ear" from using public hot tubs, saunas, and pools
Pseudomonas aeruginosa
Dangerous for cystic fibrosis and burn patients
Pseudomonas aeruginosa
Many plasmids - Very resistant to antibiotics; can metabolize disinfectants, grows in odd places like bottle caps
Pseudomonas aeruginosa
Produces pigment that can make pus appear blue-green
Pseudomonas aeruginosa
Pathogenic organism behind the reason you cannot take plants into the hospital
Pseudomonas aeruginosa
Causes plague
Yersinia pestis
Vector is the rat flea; when rats die, flea jumps to humans
Yersinia pestis
Endemic in wild rodents like squirrels, chipmunks, prairie dogs
Yersinia pestis
Has a safety pin appearance in blood smear
`Yersinia pestis
Causes bubonic plaque - organism lives and proliferates in white blood cells; lymph nodes swell and develop buboes
Yersinia pestis
Causes septicemic plague - Black death
Yersinia pestis
organism spreads to blood stream from lymph nodes and causes setpciemia and endotoxic shock; you see dark purplish patches through the skin where hemorrhages occur
Yersinia pestis
Causes "ring-a-ring of rosies"
Yersinia pestis
Causes pneumonic plague; person-to-person spread by aerosol droplets; must treat within 12-15 hrs, almost 100% mortality from untreated cases
Yersinia pestis
Called "rabbit fever" but lives in many wild rodents
Francisella tularensis
Extremely virulent - 10 organisms can cause disease
Francisella tularensis
Infected by tick bite, blood from skinning animals, inhaling organism, eating infected meat
Francisella tularensis
Bioterrorism threat
Francisella tularensis
Symptoms depend on where organism enters body
Francisella tularensis
"Cat-scratch desease" - 50% of all cats carry this bacteria in their blood
Bartonella henselae
Can be transferred by cat saliva or fleas, but most from cat bite or scratch
Bartonella henselae
Disease begins with a papule at the site of infection in 7 to 10 days
Bartonella henselae
Swells the lymph nodes, causes malaise, fever
Bartonella henselae
Usually self-limiting disease, but can be treated with antibiotics
Bartonella henselae
Among the smallest bacteria
Rickettsia
Too small to Gram stain; can't be seen with normal light microscope
Rickettsia
Obligate, intracellular organisms; can't be grown on laboratory media
Rickettsia
Diagnosed with serologically
Rickettsia
Causes typhus (purple rash), Rocky Mountain spotted fever, ehrlichiosis, anaplasmosis
Rickettsia
Causes high fever, shaking, chills, headache, nausea, vomiting - later a rash appears
Rickettsia
Arthropods are vectors (ticks, lice, fleas mainained in animal resevoir)
Rickettsia
Causes inflammation and rupture of small blood vessels
Rickettsia
Causes black measels
Rickettsia (Rickettsiosis or Rocky Mountain Spotted Fever)

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