University of Minnesota College of Pharmacy PHAR 6124 Pharmacotherapy IV Patient-Centered Pathophysiologic Approach Mark Kirstein, Pharm.D. Course Director Spring 20112 PHARMACOTHERAPY IV: Patient-Centered Pathophysiologic Approach Section Directors: Infectious Diseases: John C. Rotschafer, Pharm.D. Office: 612-624-2183 [email protected] Oncology: Mark Kirstein, Pharm.D. Office: 612-624-5689 [email protected] Toxicology: Leo Sioris, Pharm.D. Office: 952-852-4604 [email protected] Duluth: Virginia Haynes (218) 726-6025 (office) [email protected] Pharmacotherapy IV – SPRING 2011 Patient-Centered Pathophysiologic Approach WDH 7-135/LSci 165 T, Th – 10:10-12:05 Friday – 9:05 – 9:553 This course serves as an introduction to the pathophysiology and pharmacology of infectious diseases, oncologic, and toxicologic disorders. MEETING PLACE AND TIME Lectures for this course will be held in Weaver Densford 7-135 and in Duluth LSci 165 Tuesday, Thursday 10:10-12:05 and Friday 9:05-9:55 2011 INFECTIOUS DISEASES SCHEDULE Day (Date) Time Topic, Readings Lecturer Tuesday (1/18/11) 10:10-12:05 Introduction/Pharmacodynamics J. Rotschafer Thursday (1/20/11) 10:10-11:00 Aminoglycoside Pharmacokinetics J. Rotschafer 11:15-12:05 Single Daily Dose Aminoglycoside Therapy J. Rotschafer Thursday (1/20/11) Dry Run Quiz Checker 12:00pm Thurs to 12:00pm Fri Friday (1/21/11) 9:05-9:55 Therapeutic Drug Monitoring of Vancomycin J. Rotschafer Tuesday (1/25/11) 10:10-11:00 Aminoglycoside Problem Sets M. Ullman 11:15-12:05 Bacteriology M. Ullman Tuesday (1/25/11) WebVista Quiz 1 12:00pm Tues to 12:00pm Wed Thursday (1/27/11) 10:10-11:00 Antifungal Therapy M. Ullman 11:15-12:05 Vaccines M. Ullman Thursday (1/27/11) Aminoglycoside Pharmacokinetic Exam 1 12:00pm Thurs to 12:00pm Fri Friday (1/28/11) 9:05-9:55 Infection Control & Antibiotic Stewardship J. Rotschafer Tuesday (2/1/11) 10:10-11:00 Bacterial Antibiotic Resistance J. Rotschafer 11:15-12:05 Urinary Tract Infections J. Rotschafer Tuesday (2/1/11) WebVista Quiz 2 12:00pm Tues to 12:00pm Wed Thursday (2/3/11) 10:10-11:00 Lyme Disease J. Rotschafer 11:15-12:05 Meningitis J. Rotschafer Thursday (2/3/11) Aminoglycoside Pharmacokinetic Exam 2 12:00pm Thurs to 12:00pm Fri Friday (2/4/11) 9:05-9:55 Tuberculosis J. Rotschafer Tuesday (2/8/11) 10:10-11:00 Midquarter Exam J. Rotschafer 11:15-12:05 Pneumonia J. Rotschafer4 Thursday (2/10/11) 10:10-11:00 Skin & Soft Tissue Infections M. Peterson 11:15-12:05 Osteomyelitis M. Peterson Thursday (2/10/11) Aminoglycoside Pharmacokinetic Exam 3 12:00pm Thurs to 12:00pm Fri Friday (2/11/11) 9:05-9:55 Sexually Transmitted Diseases M. Peterson Tuesday (2/15/11) 10:10-11:00 Endocarditis J. Rotschafer 11:15-12:05 Intra-abdominal Infections M. Peterson Tuesday (2/15/11) WebVista Quiz 3 12:00pm Tues to 12:00pm Wed Thursday (2/17/11) 10:10-11:00 Opportunistic Infections M. Ullman 11:15-12:05 Parasitic Infections M. Ullman Friday (2/18/11) 9:05-9:55 Bioterrorism J. Rotschafer Tuesday (2/22/11) 10:10-11:00 HIV 1 H. Vezina 11:15-12:05 HIV 2 H. Vezina Tuesday (2/22/11) WebVista Quiz 4 12:00pm Tues to 12:00pm Wed Thursday (2/24/11) 10:10-11:00 HIV 3 H. Vezina 11:15-12:05 REVIEW J. Rotschafer Friday (2/25/11) 9:05-9:55 INTRO TO TOXICOLOGY L. Sioris Tuesday (3/1/11) 10:10-12:05 FINAL EXAM TOXICOLOGY SCHEDULE 2011 DAY (DATE) TIME TOPIC LECTURER Friday (2/25/11) 9:05-9:55 Toxicology Through the Ages Filandrinos Tuesday (3/1/11) 10:10-11:00 Infectious Diseases Final Exam Rotschafer 11:15-12:05 Infectious Diseases Final Exam Rotschafer Thurs. (3/3/11) 10:10-11:00 General Management and Gastric Decontamination Engebretsen 11:15-12:05 Laboratory Evaluation of the Poisoned Patient L. Sioris Friday (3/4/11) 9:05-9:55 Drugs of Abuse (Stimulants) Gualtieri Tuesday (3/8/11) 10:10-11:00 Drugs of Abuse (Opiates, hallucinogens, GHB, inhalant abuse) K. Sioris 11:15-12:05 Sedative Hypnotics/Alcohol Withdrawal K. Sioris Thursday (3/10/11) 10:10-11:00 Acetaminophen Toxicity Filandrinos 11:15-12:05 Snakes and Spiders Keyler Friday (3/11/11) 9:05-9:55 Mid-Term L. Sioris Tuesday (3/15/11) 10:10-11:00 SPRING BREAK 11:15-12:05 SPRING BREAK Thursday (3/17/11) 10:10-11:00 SPRING BREAK 11:15-12:05 SPRING BREAK5 Friday (3/18/11) 9:05-9:55 SPRING BREAK Tuesday (3/22/11) 10:10-11:00 Calcium Channel Blockers/Beta Blockers LeMaster 11:15-12:05 OTC Drug Products/Vitamins/Dietary Supplements K. Sioris Thursday (3/24/11) 10:10-11:00 Salicylates/Non-Steroidals Kingston 11:15-12:05 Toxicology Potpourri LeMaster Friday (3/25/11) 9:05-9:55 Antidepressants Gualtieri Tuesday (3/29/11) 10:10-11:00 Ethylene Glycol/Methanol LeMaster 11:15-12:05 Household Products & Carbon Monoxide L. Sioris Thursday (3/31/11) 10:10-11:00 Alcohol & Forensic Toxicology L. Sioris 11:15-12:05 One pill can kill: What every pharmacist needs to know about canine and feline pharmacology/toxicology Lee Friday (4/1/11) 9:05-9:55 OSCE Jacobson Tuesday (4/5/11) 10:10-11:00 Toxicology Final L. Sioris Date Topic Lecturer Friday 4/1/10 OSCE Tuesday 4/5/10 Toxicology Exam Sioris Tuesday 4/5/10 Introduction to Oncology Jacobson Thursday 4/7/10 Introduction to Oncology Jacobson Thursday 4/7/10 Chemotherapeutic Agents Kirstein Friday 4/8/10 Chemotherapeutic Agents Kirstein Tuesday 4/12/10 Antiemetics Lohr/Capouch Tuesday 4/12/10 Antiemetics/Mucositis Lohr/Capouch Thursday 4/14/10 Lymphoma and Quiz Jacobson Thursday 4/14/10 Colorectal Cancer Kirstein Friday 4/15/10 Oncology Complications Lohr Tuesday 4/19/10 Oncology Complications Lohr Tuesday 4/19/10 Breast Cancer Fahrenbruch Thursday 4/21/10 Breast Cancer Fahrenbruch/Capouch Thursday 4/21/10 Fever and Neutropenia Jacobson Friday 4/22/10 Exam through Oncology Complications Kirstein/Haynes Tuesday 4/26/10 Pharmacogenetics Jacobson Tuesday 4/26/10 Cancer Pain Fahrenbruch Thursday 4/28/10 Cancer Pain Fahrenbruch/Capouch Thursday 4/28/10 Gynecologic Cancers Lohr Friday 4/29/10 PHARMACY DAY – NO CLASS Tuesday 5/3/10 Prostate Cancer and Quiz Kirstein Tuesday 5/3/10 Lung Cancer Kirstein Thursday 5/5/10 Adult Leukemia Lohr Thursday 5/5/10 Hematopoietic Stem Cell Transplant Jacobson6 Friday 5/6/10 Chemotherapy Orders Kirstein/Jacobson Final Exam Week Exam (Breast Cancer through HSCT) Kirstein/Haynes COURSE OBJECTIVES Infectious Diseases The infectious diseases section of the course relates to pharmacotherapeutics and treatment of infectious diseases and