U of M PHAR 6124 - Urinary Tract Infections (50 pages)

Previewing pages 1, 2, 3, 24, 25, 26, 27, 48, 49, 50 of 50 page document View the full content.
View Full Document

Urinary Tract Infections



Previewing pages 1, 2, 3, 24, 25, 26, 27, 48, 49, 50 of actual document.

View the full content.
View Full Document
View Full Document

Urinary Tract Infections

25 views

Lecture Notes


Pages:
50
School:
University of Minnesota- Twin Cities
Course:
Phar 6124 - Pharmacotherapy IV: Patient-Centered Pathophysiologic Approach

Unformatted text preview:

Urinary Tract Infections Khalid Ibrahim Pharm D University of Minnesota Overview Urinary Tract Infections UTI Uncomplicated Complicated Prostatitis Epidemiology Approximately 7 million physician visits annually community 25 35 women ages 20 40 1 men ages 21 50 Most commonly occurring nosocomial infection UTI in children Belief that trend was underestimated in the past Prevalence ranging from 4 1 7 5 febrile children Crit Care Med 1999 May 27 5 853 4 Pediatr Clin North Am 1997 Oct 44 5 1133 69 Infect Dis Clin North Am 1997 Sep 11 3 551 81 Definitions Urinary Tract Infection UTI Cystitis M o present in the urine not accounted for by contamination Lower tract infections Pylonephritis Upper tract infections kidneys systemic Definitions cont Uncomplicated Typically in females of childbearing age No structural neurologic abnormalities interfering with urine flow Complicated Flow impedance secondary to Lesion Congenital abnormality Stone Indwelling catheter Prostatic hypertrophy Physical obstruction Neurologic deficit Definitions cont Recurrent Reinfection New organism culprit Asymptomatic bacteriuria ASB Re infection or relapse with same organism Significant bacteriuria 105 without symptoms Symptomatic abacteriuria Symptoms without 105 CFU ml Pathogen reservoirs Females urethra proximal Rectal Vaginal Males urethra distal Rectal Predisposing factors Structural abnormalities Obstruction Vesicouretral reflex Miscellaneous Catheterization Pregnancy Diabetes Residual urine Prostatic hypertrophy Tumors Anti ACH agents Calculi Neurologic disease Pathogenesis Ascending Rectal and or vaginal reservoirs Colonization of perianal area migration to perivaginal Hematogenous Lymphatic Pathogenesis cont Facilitating issues Females Reservoir s and urethra proximity Urethra length Sexual intercourse Spermicide and diaphragm Condoms Pregnancy Biofilm slime theory Bacteria interact microcolonies Small microcolonies coalesce form bacterial biofilms Glycocalyx Pathogenesis cont Facilitating



View Full Document

Access the best Study Guides, Lecture Notes and Practice Exams

Loading Unlocking...
Login

Join to view Urinary Tract Infections and access 3M+ class-specific study document.

or
We will never post anything without your permission.
Don't have an account?
Sign Up

Join to view Urinary Tract Infections and access 3M+ class-specific study document.

or

By creating an account you agree to our Privacy Policy and Terms Of Use

Already a member?