TEST 4 STUDY GUIDE Lecture 16 Gray Mater and White Mater Tracts or fasciculi are bundles of axons in the white columns o Relay same information in same direction o Ascending tracts Carry information to brain o Descending tracts Carry motor commands to spinal cord away from the brain to the effectors Spinal Cord Summary o Spinal cord has a narrow central canal surrounded by gray matter Containing sensory and motor nuclei Sensory nuclei are dorsal Motor nuclei are ventral Covered by a thick layer of white matter o Gray matter o White matter Consists of ascending and descending axons Organized in columns Contains axon bundles with specific functions o Spinal cord is highly organized possible to predict results of injuries to specific areas Spinal Nerves and Plexuses Anatomy of Spinal Nerves o Every spinal cord segment is connected to a pair of spinal nerves o Every spinal nerve is surrounded by three connective tissue layers that support structures and contain blood vessels Three Connective Tissue Layers of Spinal Nerves 1 Epineurium Outer layer o Dense network of collagen fibers 2 Perineurium Middle layer o Divides nerve into fascicles axon bundles 3 Endoneurium Inner layer o Surrounds individual axons Peripheral Nerves o Interconnecting branches of spinal nerves surrounded by connective tissue sheaths o Spinal nerves Form lateral to the intervertebral foramen at the foramen the dorsal and ventral roots unite then branch and form pathways to destination o Motor nerves Dorsal and ventral rami Dorsal ramus o Contains somatic and visceral motor fibers o Innervates the back Ventral ramus o Larger branch o Innervates ventrolateral structures and limbs o Sensory nerves o Dermatomes In addition to motor impulses dorsal and ventral rami also carry sensory information Bilateral region of skin Monitored by specific pair of spinal nerves Peripheral Neuropathy o Regional loss of sensory or motor function o Due to trauma or compression o Shingles painful rash caused by chicken pox herpes virus that travels to the dermatome served by the affected sensory nerve Virus stays dormant in neurons of the anterior gray horns after chicken pox infection Nerve Plexuses o Complex interwoven networks of nerve fibers o Formed from blended fibers of ventral rami of adjacent spinal nerves o Control skeletal muscles of the neck and limbs The Four Major Plexuses of Ventral Rami 1 Cervical plexus supplies head neck upper shoulder major nerve phrenic nerve C3 5 controls diaphragm 2 Brachial plexus supplies pectoral girdle upper limbs 3 Lumbar plexus supplies anterolateral abdominal wall genitals lower limbs 4 Sacral plexus supplies buttocks perineum lower limbs Neuronal Pools Functional Organization of Neurons o Sensory neurons Deliver information to CNS o Motor neurons Deliver commands to peripheral effectors o Interneurons Interpret plan and coordinate signals in and out About 10 million About 1 2 million About 20 billion Neuronal Pools o Functional groups of interconnected neurons interneurons o Each with limited input sources and output destinations o May stimulate or depress parts of brain or spinal cord Five Patterns of Neural Circuits in Neuronal Pools 1 Divergence 2 Convergence control of breathing 3 Serial processing 4 Parallel processing 5 Reverberation o Spreads stimulation to many neurons or neuronal pools in CNS visual info goes to visual cortex and postural balance areas o Brings input from many sources to single neuron subconscious and conscious o Moves information in single line relay of pain info o Moves same information along several paths simultaneously step onto nail you withdraw foot shift weight feel pain and scream o Positive feedback mechanism o Functions until inhibited o May help maintain consciousness muscle coordination and normal breathing Lecture 17 Reflexes Reflexes o Automatic responses coordinated within spinal cord through interconnected sensory neurons motor neurons and interneurons Produces both simple and complex reflexes Preserves homeostasis by making rapid adjustments in organs organ Each time a particular reflex is activated produces the same motor systems function response Neural Reflexes o Rapid automatic responses to specific stimuli o Basic building blocks of neural function o One o Reflex arc The wiring of a single reflex neural reflex produces one motor response Beginning at receptor Ending at peripheral effector Generally opposes original stimulus negative feedback Five Steps in a Neural Reflex o Step 1 Arrival of stimulus activation of receptor Physical or chemical changes o Step 2 Activation of sensory neuron Graded depolarization leads to action potential generation o Step 3 Information processing by postsynaptic cell Triggered by neurotransmitters o Step 4 Activation of motor neuron Action potential generated in motor neurons o Step 5 Response of peripheral effector Triggered by neurotransmitters cause skeletal muscle contraction Four Classifications of Reflexes 1 By early development Development of Reflexes 1 Innate reflexes Formed before birth a Basic neural reflexes b Ex Withdrawal from pain chewing suckling tracking 2 Acquired reflexes Learned motor patterns objects with eyes a Rapid automatic b Ex Riding a bike pressing on brakes when someone cute you off in traffic 2 By type of motor response Motor Response o Nature of resulting motor response Somatic reflexes Involuntary control of muscular system Includes a Superficial reflexes of skin mucous membranes e g plantar reflex b Stretch or deep tendon reflexes e g patellar or knee jerk reflex Visceral reflexes autonomic reflexes Control systems other than muscular system e g consensual light reflex 3 By complexity of neural circuit Complexity of Neural Circuit o Monosynaptic reflex only 1 synapse in reflex arc Sensory neuron synapses directly onto motor neuron o Polysynaptic reflex more than 1 synapse in reflex arc At least one interneuron between sensory neuron and motor neuron 4 By site of information processing Site of Information Processing o Spinal reflexes Occur in spinal cord o Cranial reflexes Occur in brain Spinal Reflexes complex o Monosynaptic reflexes o Polysynaptic reflexes o Intersegmental reflex arcs Spinal Reflexes Range in increasing order of complexity From simplest to most Many segments interact Produce highly variable coordinated motor response Remember the more synapses the slower the reaction synaptic delay Monosynaptic Reflexes o A stretch reflex o Have the least delay between sensory
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