Biology 302 Exam 3 sample questionsTrue-False ___ The chemical modification of histones, particularly by acetylation, appears to be involved in the regulation of gene expression___ Primary RNA transcripts can be used directly for translation into protein.___ The AAUAAA sequence found near the 3’-end of a mRNA is required for both terminating the transcript and for poly-adenylation.___ Conserved nucleotide sequences found in introns are required for correct RNA splicing.___One role of the 5’-UTR of a mRNA is to control mRNA stability.___ RNA polymerase II adds the poly-A tail to mRNA.___ A polyribosome is a single ribosome that is translating many mRNAs at one time.Multiple choice - Choose the correct answer 1___ Exons are parts of genes thata. are present in the mature mRNA.b. contain protein coding sequences of a gene.c. sometimes can be spliced out of a functional mRNA.d. often encode entire protein domainse. all of the above___ The addition of the poly A tail to a eukaryotic mRNA requiresa. a 3'-OH group on the RNA.b. poly A polymerase.c. a conserved sequence (AAUAAA) near the 3' end of the RNAd. ATPe. all of the above___ A new class of recently discovered small RNA molecules called microRNA (or siRNA) appear to be involved ina. RNA splicingb. the addition of the poly A tail to a mRNAc. acetylation of histone and nucleosomesd. regulating translation of mRNAe. all of the above___ The amount of histone mRNA in the cell is reduced after DNA synthesis is completed bya. increasing the level of transcription of the histone genes.b. by decreasing the rate of translation of the histone mRNA.c. by alternative splicing of the histone mRNA.d. by increasing the rate of degradation of the histone mRNA.___ Which of the following RNA molecules do you think contains a nucleotide sequence that signals transcription termination for certain genes in bacteria. a. 5'-----AUAUAUAUA-GGAUC-UAUAUAUAU---UUUUU--3'-OHb. 5'-----GCCGCCAG-GGAUC-CUGGCGGC---UUUUU--3'-OHc. 5'-----GAUGCUGC-GGAUC-GAUGCUGC---UUUUU--3'-OH2d. 5'----AUAUAUAUA-TATAAT-UAUAUAUAU---AAAAA--3'-OHb. Why? Draw a model for transcription termination in