Biology 302 Exam 1Sample questionsMultiple choice: choose the correct answer (2 pts each).___ Totipotent human stem cells can be derived froma. bone marrowb. unfertilized human eggsc. the inner cell mass of 5-day embryosd. human placentae. most human cancer cell lines___ The surface tension of water is such that a physical surface is formed that can support someweight – such as a small insect walking across a pond. This surface tension is due toa. the level of nitrates in the waterb. the fact that the sun heats the water so it doesn’t freezec. the high likelihood that there are oils floating on the surface.d. Hydrogen bonding of the water moleculese. Hydrophobic interactions of water molecules___Which of the following amino acids is a polar amino acid (there is only one in the list)?a. glycineb. valinec. aspartic acid d. tryptophane. proline___ A change in pH of a solution could have a dramatic effect on the function of a particularprotein since it coulda. alter the charge on particular amino acid R-groupsb. result in the loss of some ionic bonds between certain amino acid R-groups.c. result in the creation of some new ionic bonds between certain amino acids R-groups.d. lead to an altered folding of the protein.e. lead to any or all of the above1___ Which of the following is considered a covalent bond found in proteins a. amphipathic interactionb. hydrogen bondc. ionic bondd. di-sulfide bond e. polar/hydrophilic bond___ The primary structure of a protein refers toa. the sequence of amino acidsb. alpha helices and beta sheetsc. the overall 3-D structured. proteins formed by interactions between more than one polypeptide. ___ Motor proteins are proteins that can move bya. DNA hydrolysisb. energy derived from the breakage of peptide bondsc. non-thermodynamic principlesd. an allosteric change in their shapee. all of the above combined ____ The difference between normal prion proteins and those that cause disease is thata. they have very different primary structuresb. they have very different secondary structuresc. they have completely different nucleotidesd. they also function as virusese. the ones that cause disease now carry an RNA genome. ___ A protein that is made up of multiple protein subunits, such as hemoglobin contains aa. primary structureb. secondary structurec. tertiary structured. quarternary structuree. all of the above ___ The following variables are expected to possibly have an effect on the rate of an enzymatic reactiona. the concentration of substrate in the reaction2b. the temperature of the reactionc. the pH of the reactiond. all of the aboveTrue-False - (2 pts each):___The hydrogen-oxygen bond in water is polar, so that the oxygen atom carries a more negative charge than the hydrogen atoms.___On a very large protein, especially one that is greater than about 2,500 amino acids in length, it is highly unlikely that a mutation in any single amino acid change would have an effect on the overall 3-dimenstional structure of the protein.___ Hydrogen bonds are responsible for the primary structures of proteins.Fill in the blanks (2 points each)The cell membrane is composed of a lipid bilayer. The lipid molecules have regions that arepolar and non-polar and are therefore considered ______________.Construct/draw/link a 3 -amino acid polypeptide (5pts)3Which of the following terms relates to the finding that proteins can have functional and structural modules each expressing different functions. (circle the correct answer) 1ptAllostery checkpoint totipotent N-terminus peptide
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