Mutation as a Force of Evolution (4 pages)

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Mutation as a Force of Evolution



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Mutation as a Force of Evolution

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Discussion of how quickly mutation are introduced into population and the effects of overdominance versus underdominance. Also addressing various real life examples and how natural selection favors or selects against certain mutations.


Lecture number:
12
Pages:
4
Type:
Lecture Note
School:
Clemson University
Course:
Biol 3350 - Evolutionary Biology
Edition:
1

Unformatted text preview:

Biol 3350 1st Edition Lecture 12 Outline of Last Lecture I What is natural selection II Deviations from Hardy Weinberg Equilibrium III Measuring natural selection IV Differential survival V Differentiation fecundity VI Absolute fitness VII Relative fitness VIII Change in allele frequency due to selection Outline of Current Lecture I Outcomes of Natural Selection II Selection in natural populations a ADH is Drosophila b Desert sand and nearby ancient lava flows III Overdominance IV Cystic Fibrosis V Underdominance VI Mutation as a force of evolution VII Modeling mutation a Irreversible mutations b Reversible mutations c Equilibrium VIII Most mutation are deleterious Current Lecture I Outcomes of Natural Selection a Outcome is determined by fitness differences b Directional selection for A1A1 i A1A1 homozygote has highest fitness ii HWE is reached when p hat 1 c Directional selection for A2A2 i A2A2 homozygote has highest fitness ii HWE is reached when p hat 0 iii A1 will decrease until it becomes extinct because A2 has the highest fitness These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute II III IV iv When p hat equals 0 0 allele A1 is lost from the population Selection in natural populations a ADH is Drosophila i Fruit flies rely on sugars so they must break down ethanol in order to use the sugars ii In the control situation there was no selective pressure for a quicker ability to degrade ethanol basically a flat line iii When raised in the ethanol environment the frequency of the fast allele rose to fixation in a short amount of time only 50 generations strong selection pressure b Desert sand and nearby ancient lava flows i Light colored mice coats have much higher light reflectance ii Heterozygous condition has a little bit higher reflectance than homozygous dominant iii They looked at genotype and allele frequencies in different populations iv Shaded area on the



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