ZOL141 1st Edition Lecture 1 Outline of Last Lecture I Outline of Current Lecture II The Beginning of Human Genetics III Age of DNA IV Human Genome Project V Social and Ethical Effects of Genetics Eugenics Movement Current Lecture Definition study of inheritance as it occurs in human beings Genetic info is encoded in DNA deoxyribonucleic acid Human Genome o 3 2 billion base pairs o 3 codes for genes the rest is junk o 19 000 genes o we are 99 9 identical to our neighbor The Beginning of Human Genetics 1865 Gregor Mendel discovers basic principles of inheritance 1869 Friedrich Miescher ID s nuclein DNA associated with proteins 1925 Frederick Griffith shows that DNA is carrier of genetic info Age of DNA 1952 Rosalind Franklin shows photograph of DNA structure 1953 Watson and Crick publish model of double helix 1961 Marshall Nirenberg cracks genetic code for protein synthesis Human Genome Project 1983 First genetic disease mapped Huntington s 1990 Human Genome Project begins 1999 Chromosome 22 first human chromosome is decoded 2001 First draft of genome released 2003 Genome completed Social and Ethical Effects of Genetics Eugenics Movement Eugenics attempt to improve human species by selective breeding o Supports belief that only humans with desired traits should have kids These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute o Bad people discouraged from reproducing Flawed belief of Hereditarianism human traits are passed on with no environmental influence Real life consequences of these misconceptions o Restrictive immigration laws Immigration Restriction Act of 1924 o Restricted reproductive rights Why is Hereditarianism wrong o Most human traits are dependent on many genes and the environment o Everyone has 5 10 hidden deleterious alleles if someone has two of the same they cannot live o How do you decide which traits are desirable o breeding humans is simply unethical Other Social and Ethical Effects of Genetics o Cloning Dolly the sheep o Prenatal screening o Newborn screening o 3 parent baby