ABIO 350 Fundamental Genetics Syllabus Dr. William Jackson Spring 2007 - 1 - Instructor: Dr. William H. Jackson Office: SBDG 201A Office hours: By appointment Telephone: 641-3601 Email: [email protected] Lecture: TTH,8:00-9:15 in SBDG 200 Text: Genetics: From Genes to Genomes, 2nd Edition by Hartwell, et al. Writing Papers in the Biological Sciences., 4th Edition by McMillan Laboratory: TH, 10:50-1:30 in SBDG 104 See Laboratory Syllabus Lab Instructor: Dr. Michele Harmon Supplies: Scantron Sheets and Scientific calculator Credit: Four (4) Semester Hours Course Description: Fundamental Genetics is a four credit hour course for biology majors, which covers the principles of transmission, molecular, and population genetics. Topics covered will include Mendelian genetics, quantitative inheritance, linkage, recombination, the biochemical aspects of gene function and regulation, and developmental and population genetics. Course Objectives: This course will introduce the student to the underlying principles of genetics. It is divided into transmission and molecular genetics. On completion of this course students will be expected to 1. Demonstrate an understanding of transmission genetics; 2. Demonstrate an understanding of molecular genetics; 3. Demonstrate an ability to write and discuss applications of genetic concepts; 4. Prepare written and oral reports of data 5. Solve genetics problems using appropriate mathematical techniques in conjunction with data collected in the genetics laboratory; Attendance Policy: Students are expected to adhere to the University attendance policy as stated in the Student Handbook. In this regard, the instructor may impose a penalty for absences in excess of 25% of regularly scheduled class meetings by assigning an “F” in the course. Absences, neither excused not unexcused, absolve the student from meeting class assignments. Because of their nature, laboratory exercises cannot be made up – students should make every effort to attend all laboratory sessions. Disability Statement: If you have a physical, psychological, and/or learning disability, which might affect your performance in class, please contact the Office of Disability Services, 126A B&E (803) 641-3609, as soon as possible. The Disability Services Office will determine appropriate accommodations based on medical documentation. Methods of Presentation and Evaluation: Information will be presented through lectures, class discussions, and laboratory exercises using appropriate visual aids and laboratory equipment. Additionally, several assignments and some course materials will be handled through Blackboard. The final course evaluation will be based on the following weighted assignments: Description Percentage Comments Two 1-hr exams 30% 300 points (each exam = 15%) Genetics Problem set 15% 150 points (Transmission genetics problems) Final Exam 15% 150 points (Comprehensive final exam) Quizzes 15% 150 points (Material discussed the previous 1 – 2 weeks) Laboratory 25% 250 points See Laboratory Syllabus supplement The letter grades will be based on total accumulated points and will be assigned as follows: A>900; B>800; C>650; D>550; F<550. Biology majors must make a C or better in this core course.ABIO 350 Fundamental Genetics Syllabus Dr. William Jackson Spring 2007 - 2 - Computer Use and Email: Many, if not all of the genetics laboratory exercises will require the use of a computer. Therefore, you must be able to log on to the USCA computer system in order to accomplish these laboratory exercises. If you do not know how to sign on to the USCA computer system, you should contact the CSD HELP desk as soon as possible. All official email communications will be made to your USCA email account. This includes any messages regarding ABIO 350 announcements. In addition, instructors will not reply to emails sent from non-USCA accounts. You should get into the habit of checking your USCA email account on a regular basis. TENTATIVE LECTURE SCHEDULE Date Week Topic/Comments Chapter Jan 16 Jan 18 1 Mendel’s Breakthrough Mendel’s Breakthrough 2 3 Jan 23 Jan 25 2 Extensions to Mendel Extensions to Mendel 3 3 Jan 30 Feb 1 3 Extensions to Mendel The Chromosomal Theory of Inheritance 3 4 Feb 6 Feb 8 4 The Chromosomal Theory of Inheritance Linkage and Mapping 4 5 Feb 13 Feb 15 5 Linkage and Mapping Linkage and Mapping 5 5 Feb 20 Feb 22 6 Linkage and Mapping Exam I 5 2-5 Feb 27 Mar 1 7 DNA: Recombination and Replication Lecture Quiz 1; DNA: Recombination and Replication 6 6 Mar 6 Mar 8 8 DNA: Recombination and Replication Lecture Quiz 2; DNA: Recombination and Replication 6 6 Mar 13 Mar 15 9 Spring Break – No Classes Mar 20 Mar 22 10 DNA: Recombination and Replication Lecture Quiz 3; Gene Structure and Function 6 7 Mar 27 Mar 29 11 Gene Structure and Function Lecture Quiz 4 ; Gene Structure and Function 7 7 Apr 3 Apr 5 12 Gene Structure and Function Lecture Quiz 5; Gene Structure and Function 7 7 Apr 10 Apr 12 13 Gene Expression Exam II 8 6-7 Apr 17 Apr 19 14 Gene Expression Lecture Quiz 6; Gene Expression 8 8 Apr 24 Apr 26 15 Gene Expression Lecture Quiz 7; Gene Expression 8 8 May 8 Final Exam at 8:00 AM in SBDG 200 6-8 You will be expected to endorse the USCA HONOR PLEDGE on every assignment: 'On my honor as a University of South Carolina Aiken student, I have neither given nor received any unauthorized aid on this assignment/examination. To the best of my knowledge, I am not in violation of academic honesty'ABIO 350 Fundamental Genetics Syllabus Dr. William Jackson Spring 2007 - 3 - LABORATORY INFORMATION Instructor: Dr. Michele Harmon Office: SBDG 221A Office hours: By appointment Telephone: 641-3607 Email: [email protected] Laboratory: TH, 10:50-1:30 in SBDG 104 Text: Writing Papers in the Biological Sciences., 4th Edition by McMillan General Information: Genetics Laboratory is not separate from Genetics Lecture; therefore, students are expected to synthesize the material covered in lecture, laboratory, and the text. Each student is expected to meet every laboratory session, as it is impossible to recreate the laboratory setup after the scheduled meeting time. In general, each laboratory meeting will be divided into three sessions. The first session, lasting approximately one hour, will be used to extend lecture materials. The second session will typically be used to answer questions and solve genetics problems. The third