Molecular Biology of the CellFifth EditionChapter 13Intracellular Vesicular TrafficCopyright © Garland Science 2008Alberts • Johnson • Lewis • Raff • Roberts • WalterFigure 12-58 Molecular Biology of the Cell (© Garland Science 2008)BICD 110 Cell Biology SSII 2009The Molecular Mechanisms of Membrane Transport &Compartment DiversityTransport from the ER through the Golgi ApparatusTransport from the TRANS Golgi Network to LysosomesExocytosisEndocytosisChapter 13 - Intracellular Vesicular TrafficThe Molecular Mechanisms of Membrane Transport &Compartment DiversityTransport from the ER through the Golgi ApparatusTransport from the TRANS Golgi Network to LysosomesExocytosisEndocytosisChapter 13 - Intracellular Vesicular TrafficFigure 13-3 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-2 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-1 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-5 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-8 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-51 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-50 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-8 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-12a Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-12b Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-5 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-23b Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-24a Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-24b Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-20 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-9 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-11 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-10 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-10 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-14 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-16 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-17 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-18 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityFigure 13-22 Molecular Biology of the Cell (© Garland Science 2008)Membrane Transport & Compartment DiversityClicker questionA) TrueB) FalseComplementary Rab proteins on transport andtarget membranes dock to facilitate selectivityand docking of transport vesiclesMembrane Transport & Compartment DiversityThe Molecular Mechanisms of Membrane Transport &Compartment DiversityTransport from the ER through the Golgi ApparatusTransport from the TRANS Golgi Network to LysosomesExocytosisEndocytosisChapter 13 - Intracellular Vesicular TrafficFigure 13-3 Molecular Biology of the Cell (© Garland Science 2008)Transport from the ER through the Golgi ApparatusFigure 13-25a Molecular Biology of the Cell (© Garland Science 2008)Transport from the ER through the Golgi ApparatusFigure 13-28 Molecular Biology of the Cell (© Garland Science 2008)Transport from the ER through the Golgi ApparatusFigure 13-35 Molecular Biology of the Cell (© Garland Science 2008)Transport from the ER through the Golgi ApparatusFigure 13-30 Molecular Biology of the Cell (© Garland Science 2008)Transport from the ER through the Golgi ApparatusFigure 13-32 Molecular Biology of the Cell (© Garland Science 2008)Transport from the ER through the Golgi ApparatusFigure 13-31 Molecular Biology of the Cell (© Garland Science 2008)Transport from the ER through the Golgi ApparatusClicker question:A) TrueB) FalseComplementary Rab proteins bind ontransport vesicles and target membranes tofacilitate specificity and transport vesicledockingTransport from the ER through the Golgi ApparatusThe Molecular Mechanisms of Membrane Transport &Compartment DiversityTransport from the ER through the Golgi ApparatusTransport from the TRANS Golgi Network to LysosomesExocytosisEndocytosisChapter 13 - Intracellular Vesicular TrafficFigure 13-3 Molecular Biology of the Cell (© Garland Science 2008)Transport from the TRANS Golgi Network to LysosomesFigure 13-44 Molecular Biology of the Cell (© Garland Science 2008)Transport from the TRANS Golgi Network to LysosomesFigure 13-43 Molecular Biology of the Cell (© Garland Science 2008)Transport from the TRANS Golgi Network to LysosomesFigure 13-45 Molecular Biology of the Cell (© Garland Science 2008)Transport from the TRANS Golgi Network to LysosomesFigure 13-3 Molecular Biology of the Cell (© Garland Science 2008)Transport from the TRANS Golgi Network to LysosomesFigure 13-38 Molecular Biology of the Cell (© Garland Science 2008)Transport from the TRANS Golgi Network to LysosomesFigure 13-36 Molecular Biology of the Cell (© Garland Science 2008)Transport from the TRANS Golgi Network to LysosomesFigure 13-42 Molecular Biology of the Cell (© Garland Science 2008)Transport from the TRANS Golgi Network to LysosomesFigure 13-41 Molecular Biology of the Cell (© Garland Science 2008)Transport from the TRANS Golgi Network to LysosomesTransport from the TRANS Golgi Network to LysosomesClicker question:A) TrueB) FalseOne strict requirement for proteins leavingthe ER: they MUST be correctly foldedThe Molecular Mechanisms of Membrane Transport &Compartment DiversityTransport from the ER through the Golgi ApparatusTransport from the TRANS Golgi