Psychology 3041/6014 Spring, 2014 1 of 4 PAIN PERCEPTION 1) Phenomenon 2) Receptors & Pathway a) Nocioceptors b) Spinothalamic pathway c) Brain regions i) Thalamus ii) Hypothalamus iii) Limbic system iv) Also: Insula and anterior cingulated cortex (ACC) v) Notes:Psychology 3041/6014 Spring, 2014 2 of 4 3) Cognitive Aspects of Pain a) Expectation b) Shifting attention c) Distraction d) Individual differences e) Locus of ControlPsychology 3041/6014 Spring, 2014 3 of 4 4) Gate Control Theory a) Basics i) Melzak & Wall, 1965, 1988 ii) Note: b) Biological Circuit i) Substantia gelatinosa ii) Transmission, or T-cells in dorsal horn of spinal cord iii) Central control, necessary to explain how we can cognitively influence pain iv) Stimulus-produced analgesia (SPA)Psychology 3041/6014 Spring, 2014 4 of 4 5) Endorphins a) “Endogenous opiates” (endogenous morphine) b) Top-down circuit i) Uses endorphins to reduce pain ii) Periaqueductal gray matter iii) Nucleus Raphe Magnus iv) Spinal cord gray matter v) Transmission cells
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