Introduction to Biochemistry (CHEM 501) Spring 2009 9:00 - 9:50 am MWF, Chem 180 Instructor: Guilherme Indig Phone 229-5034; email: [email protected]; office: Chem 639. Office hours: F, 10:00 am – 1:00 pm or by appointment (to schedule an appointment, call 229-5034). No email office hours. Text: Lehninger, Principles of Biochemistry. by Nelson and Cox, 5th edition, 2008, W. H. Freeman and Company Prerequisites: Junior status, grade of C or better in Chem 221 or 223 and in chem 341 or 345. Grading: There will be three in-class exams on February 23, March 30, and May 1 with each worth 100 points. Only the two highest in-class exam grades will be used in the calculation of the final course grade (in-class exams count toward 50% of the final grade). There will be no makeup exams given. The final exam will be cumulative and will be worth 200 points (50% of the final grade). The final exam is scheduled for Wednesday, May 13, from 10:00 am to 12:00 noon. Jan. 26 Ch. 1 – Introduction March 30 Exam II 28 Ch. 2 - Water April 1 Ch. 14 – Glycolysis 30 Ch. 3 – Amino Acids and peptides 3 Ch. 14 – Gluconeogenesis Feb. 2 Ch. 3 – Protein methods 6 Ch. 14 – Penthose Phosphate Pathway 4 Ch. 4 – Protein Structure 8 Ch. 15 – Metabolic regulation 6 Ch. 4 – Protein Structure 10 Ch. 15 – Metabolic regulation 9 Ch. 5 – Protein Function 13 Ch. 16 – The Citric Acid Cycle 11 Ch. 5 - Protein Function 15 Ch. 16 – The Citric Acid Cycle 13 Ch. 6 - Enzymes 17 Ch. 17 – Fatty acid catabolism 16 Ch. 6 – Enzymes 20 Ch. 18 – Amino acid catabolism 18 Ch. 6 – Enzymes 22 Ch. 18 – Amino acid catabolism 20 Ch. 6 – Enzymes 24 Ch. 19 – Oxidative Phosphorylation Feb. 23 Exam I 27 Ch. 19 – Oxidative Phosphorylation 25 Ch. 7 – Carbohydrates 29 Ch. 19 – Oxidative Phosphorylation 27 Ch. 7 – Polysaccharides May 1 Exam III March 2 Ch. 7 – Informational carbohydrates 4 Ch. 24 – Genes and Chromosomes 4 Ch. 8 – Nucleotides and nucleic acids 6 Ch. 24 – Genes and Chromosomes 6 Ch. 8 – Nucleic acids – Structure 13 Final Exam (cumulative) 9 Ch. 10 – Lipids 11 Ch. 10 – Lipids 13 Ch. 11 – Biological Membranes 23 Ch. 11 – Membranes/Transport 25 Ch. 13 – Bioenergetics 27 Ch. 13 – Bioenergetics Department of Chemistry Policies are posted on bulletin boards across from Room 195 and adjacent to Room 164 University Policies are located online at www.uwm.edu/Dept/SecU/SyllabusLinks.pdf