BCMB 230 1st Edition Lecture 25 Outline of Last Lecture I Absorption II Lymphatic System III Control of Digestive System IV Functions of Liver V Endocrine System Outline of Current Lecture I Immune System II Inflammation III Fever Current Lecture I Immune System complex system of responses that are protective in nature defend us from infection from injury II Inflammation uncontrolled inflammation or inflammation in the wrong places can be bad life threatening basic idea is good beneficial response of body Cardinal sings of inflammation symptoms swelling redness pain localized increase in temperature What causes these symptoms increase in blood flow bring more blood to area through vasodilation increase capillary permeability fluid goes from capillaries into tissues causing swelling Anti inflammatory drugs are good to a certain point but can inhibit the body s ability to get better even if you feel better rest is the best medicine Inflammation is deadly causes a lot of chronic pain and can cause some serious physiological problems usually if it is uncontrolled or inappropriate These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute when inflammation becomes systemic all over body not localized or if it happens without chronic management not associated just with infection then we have a lot of problems Systemic vasodilation blood pressure decreases significantly very dangerous get too much of infection can get systemic vasodilation which leads to septic shock Mediators of inflammation come from variety of different cells and proteins in body act on capillaries and arterioles producing increase in capillary permeability II Fever systemic increase in temperature does this because of chemical messengers called pyrogens go to hypothalamus and raise set point of temperature regulating mechanisms pyrogens can be endogenous or exogenous endogenous something within system body doing it to ourselves exogenous something outside the system some infectious agent fever can be a good thing will selectively act on bacterial metabolism by raising temperature cause us to sequester or hide iron which the bacteria need to grow at elevated temperature bacterial growth is inhibited slow down spread or how big infectious disease is gives us a chance for other mechanisms to bring it under control fever only works on bacteria drugs such as aspirin or Tylenol also work on fever doesn t mean you want to take these drugs low fever better off just drinking plenty of fluids and getting plenty of rest
View Full Document
Unlocking...