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Neurons
- conduct electrical impulses in the nervous system -carry information in the form of action potentials over long distances -amitotic; division of cell nucleus w/o mitotic apparatus **once mature never divide again
Neuron structure
-input region; receptive or dendritic region -conducting region; carry action potentials (long distance communication part of the cell) -secretory/output region; neurotransmitter is released
Dendrite
-input region -NEVER myelinated -DO NOT conduct action potentials; instead they conduct potentials that are graded -graded potentials --> toward neuronal cell body
Cell body
-protein factor of the neuron -contains nucleus -most of the protein synthesis in the neuron occurs in the cell body
Nissl substance
-characteristic of neurons and is an elaborated form of rough endoplasmic reticulum
Axon/conducting region
-extends from cell body -end of action potential; axons branch extensively to innervate other neurons, muscle fibers, or glands (telodendria)
Action potentials
-all or none electrical signals that provide rapid communication in neurons over long distance **trigger zone is the site of action potential initiation
Telodendria
forms the axon terminals
Axon terminals
-secretory regions of the neuron; form the presynaptic portions of the neuron which release neurotransmitter onto the postsynaptic cell
Sensory neurons (afferent)
-Found in both peripheral and CNS
Motor neurons (efferent)
-Can be found in both peripheral and CNS -carry information toward the effector organs
Associative (interneurons)
-confined to CNS
3 types of glial cells in CNS
**All neuronal and glial cells originated embryologically as neuroectodermal cells; except for microglial cells 1. Astrocytes, cells with many processes giving them a star-like appearance 2. Oligodendrocytes, cells with few (oligo) branches (dendro) 3. Microglial cells;
Ependymal cells
**supporting cells in CNS, not usually glial cells -form an epithelium that lines the ventricles of the brain -responsible for moving the cerebrospinal fluid with beating cilia
Astrocytes
-regulates the concentration of ions, particularly K+ by pumping ions -regulates the concentration of neurotransmitters in the extracellular space since neuronal activity can also lead to increases in the extracellular concentration of neurotransmitters - wrapped around capillaries;…
Extracellular space
-space between the cells
Oligodendrocytes
-in CNS -responsible for forming the myelin sheaths around axons; Myelin forms the insulating layers around neurons so that the action potentials can conduct more rapidly -responsible for forming the white matter in the CNS -can envelope several axons and wrap them with myelin
Myelination
-proceeds when processes of oliogodendrocytes wraps around the axon forming layer upon concentric layer of myelin

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