Alternative CD TechnologiesMusic and BeyondProtein DetectorsBio-CD’s :RevolutionaryHow It Works?Making Bio-Cd’s RealityMicrolaboratoryMicrostructuresSlide 9ImmunoassaysProtein QuantificationCD DetectorNerve Gas DetectorBackgroundComponentsCD ConnectionSlide 17Scent Stories??Not A CD Technology!Questions?ReferencesAlternative CD Alternative CD TechnologiesTechnologiesBy James WrayBy James WrayMusic and Beyond Music and Beyond CD’s presently used for Music and DataCD’s presently used for Music and DataOther Technologies:Other Technologies:Protein DetectorsProtein DetectorsMicrolaboratoriesMicrolaboratoriesImmunoassaysImmunoassaysNerve Gas DetectorsNerve Gas DetectorsProtein DetectorsProtein DetectorsProteins are found throughout the human Proteins are found throughout the human body and are involved in all functions.body and are involved in all functions.Blood Proteins - Markers for Different Blood Proteins - Markers for Different DiseasesDiseasesPresent Technology:Present Technology:CostlyCostlySamples are sent to LabsSamples are sent to LabsOnly detect a few proteinsOnly detect a few proteinsBio-CD’s :RevolutionaryBio-CD’s :RevolutionaryDavid Nolte –Purdue UniversityDavid Nolte –Purdue UniversityEnable in office testingEnable in office testingRequire a drop of bloodRequire a drop of bloodTest for over 10,000 proteinsTest for over 10,000 proteinsAnalog rather then Digital ResultsAnalog rather then Digital ResultsTake 15 secondsTake 15 secondsHow It Works?How It Works?CD’s have Pits:CD’s have Pits:Each pit would contain thousands of detector Each pit would contain thousands of detector chemicalschemicalsEach track would have a different chemicalEach track would have a different chemicalAbout 10,000 tracks availableAbout 10,000 tracks availableConcentration of Proteins could be Concentration of Proteins could be determineddeterminedSensitivity – 10 nanograms/ml Sensitivity – 10 nanograms/ml Uses a laser to detect concentrationUses a laser to detect concentrationMaking Bio-Cd’s RealityMaking Bio-Cd’s RealityRefine the process of depositing the Refine the process of depositing the chemical detectors on the tracks of the CDchemical detectors on the tracks of the CDCould take 10 yearsCould take 10 yearsMicrolaboratoryMicrolaboratoryCD’s have Microstructures embeddedCD’s have Microstructures embeddedSamples deposited at center of CDSamples deposited at center of CDCentrifugal force drives samples and Centrifugal force drives samples and reagents through the microstructuresreagents through the microstructuresReduces time for experimentsReduces time for experimentsUsed for preparing samples that will be Used for preparing samples that will be analyzed lateranalyzed laterMicrostructuresMicrostructures104 MicrostructuresImmunoassaysImmunoassaysProtein QuantificationProtein QuantificationUsed to determine protein concentrationsUsed to determine protein concentrationsSmaller scale then Bio-CD’s- Structures Smaller scale then Bio-CD’s- Structures are largerare largerUses laser to activate and detect Uses laser to activate and detect fluorescence of markersfluorescence of markersCD DetectorCD DetectorNerve Gas DetectorNerve Gas DetectorBackgroundBackgroundUsed to detect various nerve gasesUsed to detect various nerve gasesSarinSarinSominSominGFGFEnable inexpensive, small units to be Enable inexpensive, small units to be deployed on a large-scale by police and deployed on a large-scale by police and soldiers.soldiers.Used to track presence and movement of Used to track presence and movement of gas after an explosiongas after an explosionComponentsComponentsUses a silicon wafer to detect compounds Uses a silicon wafer to detect compounds with a phosphorous-flourine chemical with a phosphorous-flourine chemical bondbondIt breaks the bond in the nerve gas, which It breaks the bond in the nerve gas, which emits hydrogen flouride gas which is used emits hydrogen flouride gas which is used to etch and frost glass.to etch and frost glass.Optical coating on wafer changes color in Optical coating on wafer changes color in the presence of the gasthe presence of the gasCD ConnectionCD ConnectionUses a laser from a CD player to detect color Uses a laser from a CD player to detect color changeschangesLow Cost - prototype constructed from a $24 CD Low Cost - prototype constructed from a $24 CD playerplayerMore sensitive than surface acoustic-wave More sensitive than surface acoustic-wave devices used presentlydevices used presentlyDetects Parts Per BillionDetects Parts Per BillionMore reliable- other device has a lot of false-More reliable- other device has a lot of false-alarmsalarmsCan also be used as an inexpensive dosimeterCan also be used as an inexpensive dosimeterScent Stories??Scent Stories??New Product- From the Febreeze Co.New Product- From the Febreeze Co.Claims to be “Like A CD”Claims to be “Like A CD”Technology – appears to be like a CDTechnology – appears to be like a CDRoundRoundSpinsSpinsVery slowlyVery slowlyNot A CD Technology!Not A CD