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VANDERBILT HON 182 - Study Notes

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Week 2Week 3Week 4Week 5Week 7Week 8Weeks 9-12Weeks 13-16Week 20Week 24Weeks 25 - 28Weeks 29 - 32Weeks 38 - 40First Trimester:This remarkable photograph of a tiny fetus in its unruptured amniotic sac was taken after surgery for an ectopic pregnancy in 1972. This picture demonstrates the development of ababy at only six weeks after conception.Photograph by University of Minnesota Medical Photographer, Robert Wolfe.Week 2Fertilization, the joining of the sperm and the egg in the fallopian tube (below) to form a unique human being, occurs. Forty-six chromosomes provide the blueprint for the embryo’s physical characteristicThe picture on the right is a fertilized egg only thirty hours after conception. Magnified here, it is no larger than the head of a pin. Still rapidly dividing, the developing embryo, called a zygote at this stage, floats down from the fallopian tube and towards the uterus.Week 3At this point, the blastocyst, or developing embryo, is looking for a spot to implant in the uterus. Early formation of the central nervous system, backbone, and spinal column has begun. The gastrointestinal system has also begun to develop with the kidneys, liver, and intestines forming. The heart has begun to form.Week 4Hormones produced by the embryo stop the mother’s menstrual cycle.Week 5The embryo’s tiny heart begins to beat by day twenty-one. The brain has developed into 5areas and some cranial nerves are visible. Arm and leg buds are visible and the formation of the eyes, lips, and nose has begun. The spinal cord grows faster than the rest of the body giving a tail like appearance which disappears as the embryo continues to grow. Theplacenta begins to provide nourishment for the embryo.Week 7Major organs have all begun to form. The embryo has developed its own blood type, unique from the mother’s. Hair follicles and nipples form and knees and elbows are visible. Facial features are also observable. The eyes have a retina and lens. The major muscle system is developed and the embryo is able to move.Week 8The embryo is reactive to its environment inside the amniotic sac where it swims and moves. Hands and feet can be seen. At the end of week 8, the embryonic period is over and the fetal stage begins.Weeks 9-12The heart is almost completely developed and the heart rate can be heard on a Doppler machine at the doctor’s office. Most major organs and tissues have developed and red blood cells are now produced in the liver. The face is well formed and the eyes are almostfully developed. The eyelids will close and not reopen until the 28th week. Arms, hands, fingers, legs, feet, and toes are fully formed. Nails and earlobes start to form and tooth buds develop in the gums. Fetus can make a fist with its finger. Testosterone (male sex hormone) is produced by the testes in male fetus.2nd Trimester18 weeks gestation (16 weeks since conception)“Life is present from the moment of conception.”Dr. Jerome Lejeune, late professor and world renowned geneticist, University of Descarte, Paris“A person’s a person, no matter how small!”Excerpted from “Horton Hears a Who,” by Dr. Seuss, late famous children’s authorWeeks 13-16The brain is fully developed and the fetus can suck, swallow, and make irregular breathing sounds. Fetus can feel pain (New England Journal of Medicine). Fetal skin is almost transparent. Muscles tissue is lengthening and bones are becoming harder. Liver and organs produce appropriate fluids. Eyebrows and eyelashes appear and the fetus makes active movements including kicks and even somersaults.Week 20“Quickening” (when the mother can feel the fetus moving) usually occurs around this time. Finger and toenails appear. Lanugo, a fine hair now covers the entire body. The fetus can hear and recognize the mother’s voice. Sex organs are visible on ultrasound devices.Third Trimester:Week 24A protective waxy substance called Vernix covers the skin. By birth, most of the Vernixwill be gone but any that is left is quickly absorbed. Fetus has a hand and startle reflex. Footprints and fingerprints are forming. Fetus practices breathing by inhaling amniotic fluid into its developing lungs.Weeks 25 - 28Rapid brain development occurs during this period and the nervous system is able to control some bodily functions. The fetus’ eyelids now open and close. At 25 weeks there is a 60% chance of survival if born. The fetus is considered legally viable at 28 weeks and there is a 90% chance of survival if born at this point.Weeks 29 - 32There is a rapid increase in the amount of body fat the fetus has. Rhythmic breathing occurs, but the lungs are not yet mature. The fetus sleeps 90-95% of the day. At this point there the survival rate is above 95% if the baby is born.Weeks 38 - 40The fetus is considered full-term. Lanugo is gone except on upper arms and shoulders. Hair on the baby’s head is now coarser and thicker. The lungs are mature. The average weight of the baby at this point is seven and a half pounds. At birth the placenta detaches from the uterus and the umbilical cord will be cut as the baby takes his first breaths of air.Breathing will trigger changes in the heart and bypass arteries forcing all blood to now travel through the


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