MCB 150 1st Edition Lecture 6 Outline of Last Lecture I. Introduction to proteinsII. Amino Acid PropertiesIII. Structuresa. Primaryb. Secondaryc. Tertiaryd. QuaternaryOutline of Current Lecture IV. Enzymesa. Endergonicb. ExergonicV. Activation energyVI. Irreversible inhibitorsCurrent LectureEnzymes:Enzyme: biological catalyst that facilitate biological reactions. Many reactions need enzymes because they react at such a slow rate. Endergonic: reactions that require energy.- Ex. Linking together small molecules into larger ones (condensation reactions)Exergonic: reactions that release energyThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.- Break down larger molecules into smaller ones (hydrolysis)Spontaneous: a reaction that releases energy, mostly in the form of heatCatabolic reactions: require a certain amount of energy to get started, or Energy of Activation.Enzymes bind certain specific substrates to their active sites, they cause the substrate to changeduring the process but they themselves do not change. How do enzymes decrease Activation Energy?- The act as templates for substrate orientation - Stressing the substrates and stabilizing the transition state- Participating directly in the reaction- Enzymes are not changed by the reaction in which they participate inIrreversible inhibitors:- Permanently attach to or alter the active site of the enzyme and prevent future catalysis by that