MCB 150 1st Edition Lecture 6 Outline of Last Lecture I Introduction to proteins II Amino Acid Properties III Structures a Primary b Secondary c Tertiary d Quaternary Outline of Current Lecture IV Enzymes a Endergonic b Exergonic V Activation energy VI Irreversible inhibitors Current Lecture Enzymes Enzyme biological catalyst that facilitate biological reactions Many reactions need enzymes because they react at such a slow rate Endergonic reactions that require energy Ex Linking together small molecules into larger ones condensation reactions Exergonic reactions that release energy These notes represent a detailed interpretation of the professor s lecture GradeBuddy is best used as a supplement to your own notes not as a substitute Break down larger molecules into smaller ones hydrolysis Spontaneous a reaction that releases energy mostly in the form of heat Catabolic reactions require a certain amount of energy to get started or Energy of Activation Enzymes bind certain specific substrates to their active sites they cause the substrate to change during the process but they themselves do not change How do enzymes decrease Activation Energy The act as templates for substrate orientation Stressing the substrates and stabilizing the transition state Participating directly in the reaction Enzymes are not changed by the reaction in which they participate in Irreversible inhibitors Permanently attach to or alter the active site of the enzyme and prevent future catalysis by that enzyme