Discussion 2 in class activity Form groups and work through these questions together Feel free to use the internet your notes or any other resource that is helpful in answering these questions Ask your TA or UTA if you re stuck You ll go over these questions at the end of your discussion section If you finish early begin working on the discussion homework which is due by Sunday night 1 Phosphorylation and dephosphorylation are important processes in cell signaling and one way that proteins such as enzymes or transcription factors are turned on and off a What does phosphorylation mean b What is the source of the phosphate c How does phosphorylation lead to changes in protein activity d What type of macromolecule DNA lipid carbohydrate or 2 Find one example of a stem cell that could be found in a non pregnant adult human body Where is this protein is a phosphatase e What does a phosphatase do cell found What role does it play What is its level of potency 3 What does gene expression mean 1 Discussion 2 in class activity Use this diagram for the following question S Signal R Receptor TK1 tyrosine kinase 1 PO4 phosphate group TK2 tyrosine kinase 2 TFa transcription factor a RNAp RNA polymerase The cells above show a receptor kinase pathway without a signal present left and with the signal right You analyze cells with this pathway and observe the following results The receptors are present TK1 molecules are not phosphorylated TFA molecules are in the cytoplasm and inactive Is this signal bound to the receptor either currently or very recently Explain your answer in one sentence 2
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