DOSAGE: PO 10 mg TID; max 40 mg/dayPT EDUCATION: take medication as directed, first does should be taken shortly after waking up, second dose at midday, third dose before evening meal and at least 4 hours before bedtime.; take missed dose as soon as remember unless almost time for next dose – do not double dosesFC: Adrenergic agonist TU: vasopressor USE: tx symptomatic orthostatic hypotension FC: Coronary vasodilator; antianginal CC: Nitrate – affects how bld carries oxygen TU: Prevention of anginal attack USE: Chronic stableangina pectoris, prophylaxis of angina pain, HF associated with acute MI, controlled hypotension in surgical procedures, anal fissuresNAME: Nitroglycerin (Rx) DOSAGE: Adult: SL dissolve tab under tongue when pain begins; may repeat q5min until relief occurs; take no more than 3 tab/15 min; use 1 tab prophylactically 5-10 min before activities; SUS REL cap q6-12hr on empty stomach; TOP 1-2 inches q8hr; increase to 4 in q4hr as needed; IV 5 mcg/min, then increase by 5 mcg/min q3-5min; if no response after 20 mcg/min, increase by 10-20 mcg/min until desired response; transdermal apply a patch daily to a site free from hair; remove patch at bedtime to provide 10-12 hr nitrate-free interval to avoid tolerancePT EDUCATION : avoid alcohol, product may cause headache; tolerance usually develops; use nonopioid analgesic, product may be taken before stressful activity, exercise, sexual activity, SL tab may sting when product comes in contact with mucous membranes, Caution patient to avoid hazardous activities if dizziness occurs, Instruct patient to comply with complete medical regimen, Advise patient to make position changes slowly to prevent fainting, Advise patient to never use erectile dysfunction products (sildenafil, tadalafil, vardenafil); may cause severe hypotension, deathNAME: Midodrine / ProAmatineNURSING CONSIDERATIONS: [1] report immediately to physician sensations a/w supine hypotension (I.e pounding in ears, headache, blurred vision, awarenessof heart beating). [2] d/c drug and report to physician if s/s of bradycardia develop (i.e dizziness, pulse slowing, fainting) [3] monitor regular supine and standing BP. Stop if supine BP increases excessively; determine acceptable parameters [4] monitor all patients closely for behavior changes. [5] monitor carefully effect of the drug in diabetics with orthostatic hypotension and those taking flu cortisone acetate, which may increase IOPACTION: activates the alpha-adrenergic receptors of the arteries and veins, resulting in increased vascular tone and increased blood pressureSIDE EFFECTS: (common) Headache, mild tremors,nervousness, dizziness (toxic) seizures from excessive CNSstimulation, hypotension or hypertension, dysrhythmias,palpitations, fatigue, malaise, insomnia, dry mouth, nausea –two most life threatening effects involve CNS and CV systemANTIDOTE: manage the symptoms and support ptNURSING CONSIDERATIONS: [1] Monitor orthostatic B/P, pulse[2[ Assess pain: duration, time started, activity being performed, character; check for tolerance if taken over long period[3] Monitor for headache, light-headedness, decreased B/P; may indicate a need for decreased dosageACTION: Decreases preload and afterload, which thus decreases left ventricular end-diastolic pressure and systemic vascular resistance; dilates coronary arteries and improves blood flow through coronary vasculature, dilates arterial, venous beds systemicallySIDE EFFECTS: Headache, flushing, dizziness, postural hypotension, tachy, Collapse, syncope, palpitations, nausea, vomiting, pallor, sweating, rashNAME: Hydrocerin Cream / Lanolin alcoholNAME: Pramipexole (Rx) / MirapexFC: Emollient USE: moisturizer to treat or prevent dry, rough, scaly, itchy skinand minor skin irritations (such as diaper rash, skin burns from radiation therapy).FC: Antiparkinsonian Agent CC: Dopamine receptor agonist (activates dopamine), non-ergot. TU: Decreased symptoms of Parkinson’s disease (involuntary movements) USE: Idiopathic Parkinson’s disease, restless leg syndrome DOSAGE: Use as directedPT EDUCATION: Follow all the directions on the label for proper use. Apply to the skin only. Avoid sensitive areas such as your eyes, inside your mouth/nose, and the vaginal/groin area, unless the label or your doctor directs you otherwise. Checkthe label for directions about any areas or types of skin where you should not apply the product (such as on the face, any areas of broken/chapped/cut/irritated/scraped skin, or on a recently shaved area of the skin).DOSAGE: Initial treatment Adult: PO from a starting dose of 0.375 mg/day given in 3 divided doses, increase gradually by 0.125 mg/dose at 5-7–day intervals until total daily dose of 4.5 mg is reached; ER 0.375 mg qd, may increase up to 0.75 mg/day, then increments of 0.75 mg/day ≤5-7 days, max 4.5 mg/day Restless leg syndrome Adult: PO 0.125 mg 2-3 hr before bedtime, increase gradually, max 0.5 mg/dayPT EDUCATION: Advise patient that therapeutic effects may take several wk to a few mo, change positions slowly to prevent orthostatic hypotension, product exactly as prescribed; if product is discontinued abruptly, parkinsonian crisis may occur; if treatment is to be discontinued, taper over 1 wk; avoid alcohol, OTC sleeping products, Teach patient to notify prescriber of impulse control disorders: shoppingACTION: Selective agonist for D2 receptors (presynaptic/postsynaptic sites); binding at D3 receptor contributes to antiparkinson effectsSIDE EFFECTS: Agitation, insomnia, psychosis, hallucinations, depression, dizziness, headache, confusion, amnesia, dream disorder, asthenia, dyskinesia, hypersomnolence, sudden sleep onset, impulse-control disorders, Orthostatic hypotension, edema, syncope, tachycardia, increased B/P, heart rate, Blurred vision, antidiuretic hormone secretion (SIADH), nausea, anorexia, constipation, dysphagia, dry mouth, impotence, urinary frequency, hemolytic anemia, leukopenia, agranulocytosis, PruritusNURSING CONSIDERATIONS: [1] Monitor B/P, ECG, respiration during initial treatment; hypo/hypertension should be reported [2] Assess mental status: affect, mood, behavioral changes, depression; complete suicide assessment [3]Assess for involuntary movements in parkinsonism: akinesia, tremors, staggering gait, musclerigidity, drooling; these symptoms should improve with therapy [4] Assess for sleep attacks: may fall asleep during activities, without warning; may need