Chapter 25 Liver Gallbladder Pancreas Liver Composed of 4 lobes left right quadrate caudrate Weighing in at around 3 pounds the liver is the body s second largest organ only the skin is larger and heavier The liver performs many essential functions related to digestion metabolism immunity and the storage of nutrients within the body These functions make the liver a vital organ without which the tissues of the body would quickly die from lack of energy and nutrients Fortunately the liver has an incredible capacity for regeneration of dead or damaged tissues it is capable of growing as quickly as a cancerous tumor to restore its normal size and function Gallbladder and Bile Located on underside of the liver Stores and concentrates bile from liver Bile contains bilirubin from hemoglobin and bile salts and lecithin that allow for fat digestion 500 1 000 ml a day 80 reabsorbed in small intestine intrapathcirculation Pancreas Located behind the stomach 12 15 cm long Exocrine portion secretes pancreatic juice into the pancreatic duct 1 200 ml to The pancreatic duct joins the bile duct at the hepatopancreatic sphincter The hepatopancreatic sphincter controls release pf pancreatic juice and bile into Zymogens are enzymes that are inactive until in their environment of work 1 500 ml the duodenum Pancreatic Zymogens Trypsinogen into trypsin digest proteins Chymotrypsinogen into chymotryspin digest proteins Other enzymes pancreatic amylase digest starch Pancreatic lipase digest fats Dexoyribonuclease and ribonuclease digest DNA and RNA respectively Pancreatic secretion 1 Ach prepares for food 2 Ckic causes bile secretion 3 Secretion causes NaHCO3 secretion neutralizes pH
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