PGY452 552 Spring 2013 Endocrinology Dr Michael Morales Office 202 Cary Hall Hours by appointment Office Phone 829 3965 E mail moralesm buffalo edu If you have questions please E mail me and put PGY452 question in the subject line so that I ll be sure to notice Office hours are by appointment Good questions will be posted on the PGY452 endocrine blog 1 Tips for Printing Although I use a lot of color an animation these slides can be printed using a black white laser printer For best results 1 I intended for you to use the Handout View at two slides per page in portrait orientation If you choose 4 or 6 slides the text may be too small to read 2 On the bottom of the print menu select Color or Grayscale Selecting Pure Black White gives results that are difficult to read Color or Gray Scale Pure B W 2 Navigating Presentations Look out for icons at the bottom of the screen Notes Material for which you ll be responsible will be on next page Definitions for which you are responsible will be at the end Hints Tips Just filling in a few blanks also at the end Heavily animated slide Handouts are not meant to be a text book if you don t listen to the lectures take notes they will not make sense 3 Want to ask questions after class A good time to find me I happy to answer them outside in the lobby 4 Good questions will be posted to the UBLearns course blog which is not up yet 5 Key to symbols Single reaction Pathway multiple reactions Transport Change enzyme levels by regulation of gene expression Substrate Product Substrate Product Activity change protein kinase activity Substrate Product activity complex stimuli 6 Textbook You are not directly responsible for material in the text Please take a look at Chapters 1 3 https www clinicalkey com It might help to read it Definitions Basic anatomy Especially reproductive endocrinology If this material does not look familiar to you please study it carefully I m assuming you know it 7 Exam 1 how to do well on it Now that I have your attention A study guide will be posted Does not replace Lectures Notes Understanding the material Previous questions from the last two years That s everything deleted the bad not representative repetitive Test emphasis might not be the same If the only thing you study is last year s test you are probably in big trouble 8 Still more testing Unless I say otherwise you will not be expected to memorize Abbreviations ACTH adrenocorticotropin the exam will include a table Details of structures Details of synthetic pathways Some exceptions However you should have enough familiarity with the above so that I can refer to them in a question without you going into shock You will understand when you see the practice test The best students are able to take information from several topics and combine it into new information See the big picture 9 Exam 1 will cover topics 1 14 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 Hormones Endocrine signaling Regulation of the endocrine system Complex inputs and the central nervous system Quick overview of whole body metabolism Short term metabolic control by insulin glucagon Regulation of long term energy stores Diabetes the Metabolic Syndrome Growth hormone and IGF1 the other face of anabolism Thyroid hormone Cortisol the slow stress response Epinephrine the fast stress response Endocrine regulation of ECF osmolarity Calcium homeostasis Male reproductive endocrinology fetal differentiation Female reproductive endocrinology Lactation Exam 1 review session Exam 1 Chapt 1 31 1 31 2 2 2 2 2 7 1 3 37 3 37 40 40 38 2 7 38 2 9 2 9 38 38 2 14 40 2 16 2 16 2 21 2 21 2 21 41 42 42 42 39 2 23 43 2 23 43 2 28 43 2 28 Thursday March 2 The fnal will cover 1 4 plus 15 17 PRELIMINARY LECTURE SCHEDULE Topic Date 10 One more time Exam 1 Final Topics 1 4 Topics 5 14 Exam 1 ONLY Properties of hormones in Topics 15 17 See the study guide practice test REVIEW session on 2 23 is informal You ask questions I answer questions Topics 15 17 11 questions Topics 1 4 6 questions Late in the semester I will give you a study guide for the fnal The test questions Yes the actual test questions Not the answers