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U of A CHEM 2613 - Exam 2 Study Guide

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CHEM 2613 1st EditionExam # 2 Study Guide Lecture 1: (February 13) SN1 and SN2 Reactions- Nucleophilic Aliphatic Substitution: SN2SN2 reactions occur in one step. The step is rate determining as far as transition state of the nucleophile and leaving group. They produce backside attack first and are accelerated in polar aprotic solvents.- Nucleophilic Aliphatic Substitution: SN1An SN1 occurs in two steps. Step one is a slow rate determining ionization of the C-X bond toform an carbocation intermediate, followed by step two by rapid reaction with a nucleophile. It gives a racemic mixture. They are accelerated in polar protic solvents. 1.) How can SN1 and SN2 be predicted based on experimental conditions?Lecture 2: (February 18)β-Elimination: E1- E1 reactions involve the elimination of atoms or groups of atoms from adjacent carbons. Thisreaction occurs in two steps. Involves a carbocation intermediate and the leaving group leavesfirst.β-Elimination:E2- E2 reaction occurs in one step. A hydrogen is removed forcing leaving group to leave with theformation of an alkene.2.) Write structural formulas for these common organic solvents:(a) Dichloromethane(b) Acetone(c) EthanolThese notes represent a detailed interpretation of the professor’s lecture. GradeBuddy is best used as a supplement to your own notes, not as a substitute.(d) Diethyl ether3.) Arrange these aprotic solvents in order of increasing polarity:(a) Acetone(b) Pentane(c) Diethyl ether(d) Pentane4.) Arrange these protic solvents in order of increasing polarity:a.) H2Ob.) CH3OH c.) CH3CH2OH Lecture 3: February 235.) What is a dehydration reaction?6.) What is the rule of thumb for solubility of alcohols?7.) Know the rules of naming salts.Lecture 4: (February 25)8.) Draw the structural formula of the product formed by treating cyclohexene oxide with aqueous acid. 9.) What are thiols? What is its functional group?10.) Show how to convert 1, 2 dimethylcyclohexene to trans-1,2 dimethylcyclohexane-1,2-diol.11.)What are the characteristic reactions of thiols?12.) What are Huckel’s rules?13.) Know the four aromatic hydrocarbons discussed in the book.Lecture 5: (February 27)14.) Know the five membered- ring compounds furan, pyrrole, and imidazole.15.) Draw the following compounds. Assign name locators on each one.a. 4-Bromotolueneb. 3-Chloroanilinec. 1,3- Dimethylbenzened.


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U of A CHEM 2613 - Exam 2 Study Guide

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